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- W2045990864 abstract "Bile salts (BS) are bio-surfactants present in the gastrointestinal tract (GIT) that play a crucial role in the digestion and absorption of nutrients. The importance of BS for controlled release and transport of lipid soluble nutrients and drugs has recently stimulated scientific interest in these physiological compounds. BS are so-called facial amphiphiles showing a molecular structure that is very distinct from classical surfactants. This peculiar molecular structure facilitates the formation of dynamic aggregates able to solubilise and transport lipid soluble compounds. The detergent nature of BS has been studied in the literature, mostly concentrating on the self-assembly behaviour of BS in solution but also in relation to protein denaturation and its effect on improving proteolysis. In contrast, the affinity of BS for hydrophobic phases has received less attention and studies dealing directly with the interfacial behaviour of BS are very limited in the literature. This is despite the fact that the interfacial activity of BS plays a vital role in fat digestion since it is closely involved with lypolisis. BS adsorb onto fat droplets and can remove other materials such as proteins, emulsifiers and lipolysis products from the lipid surface. The unusual surface behaviour of BS is directly related to their intriguing molecular structure and further knowledge could provide an improved understanding of lipid digestion. This review aims to combine the new insights gained into the surface properties of BS and their role in digestion. A better understanding of surface activity of BS would allow manipulation of physico-chemical and interfacial properties to modulate lipid digestion, improve bioavailability of lipid soluble nutrients and reduce absorption of saturated fats, cholesterol and trans fats." @default.
- W2045990864 created "2016-06-24" @default.
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- W2045990864 date "2011-06-01" @default.
- W2045990864 modified "2023-10-16" @default.
- W2045990864 title "The role of bile salts in digestion" @default.
- W2045990864 cites W1900721369 @default.
- W2045990864 cites W1902233018 @default.
- W2045990864 cites W1965102288 @default.
- W2045990864 cites W1966196337 @default.
- W2045990864 cites W1966415822 @default.
- W2045990864 cites W1969076903 @default.
- W2045990864 cites W1969770630 @default.
- W2045990864 cites W1974616640 @default.
- W2045990864 cites W1976119364 @default.
- W2045990864 cites W1977244938 @default.
- W2045990864 cites W1978147337 @default.
- W2045990864 cites W1978809552 @default.
- W2045990864 cites W1986262374 @default.
- W2045990864 cites W1986733014 @default.
- W2045990864 cites W1990432963 @default.
- W2045990864 cites W1991653857 @default.
- W2045990864 cites W1994142612 @default.
- W2045990864 cites W1997390238 @default.
- W2045990864 cites W1997761534 @default.
- W2045990864 cites W2007125578 @default.
- W2045990864 cites W2010765808 @default.
- W2045990864 cites W2015548166 @default.
- W2045990864 cites W2022375711 @default.
- W2045990864 cites W2022558307 @default.
- W2045990864 cites W2022711127 @default.
- W2045990864 cites W2034211794 @default.
- W2045990864 cites W2034644440 @default.
- W2045990864 cites W2035420075 @default.
- W2045990864 cites W2039075832 @default.
- W2045990864 cites W2040802315 @default.
- W2045990864 cites W2044429169 @default.
- W2045990864 cites W2045283008 @default.
- W2045990864 cites W2047281591 @default.
- W2045990864 cites W2051960512 @default.
- W2045990864 cites W2052878201 @default.
- W2045990864 cites W2054905787 @default.
- W2045990864 cites W2058831301 @default.
- W2045990864 cites W2061498932 @default.
- W2045990864 cites W2066318957 @default.
- W2045990864 cites W2066490668 @default.
- W2045990864 cites W2068177799 @default.
- W2045990864 cites W2068584767 @default.
- W2045990864 cites W2069963367 @default.
- W2045990864 cites W2078257736 @default.
- W2045990864 cites W2079478816 @default.
- W2045990864 cites W2081013444 @default.
- W2045990864 cites W2081264168 @default.
- W2045990864 cites W2084224847 @default.
- W2045990864 cites W2086461626 @default.
- W2045990864 cites W2091084349 @default.
- W2045990864 cites W2091708237 @default.
- W2045990864 cites W2095546951 @default.
- W2045990864 cites W2103613210 @default.
- W2045990864 cites W2105834748 @default.
- W2045990864 cites W2106407832 @default.
- W2045990864 cites W2115162513 @default.
- W2045990864 cites W2129222597 @default.
- W2045990864 cites W2140382469 @default.
- W2045990864 cites W2156968573 @default.
- W2045990864 cites W2157342146 @default.
- W2045990864 cites W2158608791 @default.
- W2045990864 cites W2169356020 @default.
- W2045990864 cites W2171070582 @default.
- W2045990864 cites W2184631836 @default.
- W2045990864 cites W2322339907 @default.
- W2045990864 doi "https://doi.org/10.1016/j.cis.2010.12.002" @default.
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