FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2045997611> ?p ?o ?g. }

• W2045997611 endingPage "3024" @default.
• W2045997611 startingPage "3013" @default.
• W2045997611 abstract "Synthetic polymers have attracted much attention in tissue engineering due to their ability to modulate biomechanical properties. This study investigated the feasibility of processing poly(ɛ-caprolactone) (PCL) homopolymer, PCL-poly(ethylene glycol) (PEG) diblock, and PCL-PEG-PCL triblock copolymers into three-dimensional porous scaffolds. Properties of the various polymers were investigated by dynamic thermal analysis. The scaffolds were manufactured using the desktop robot–based rapid prototyping technique. Gross morphology and internal three-dimensional structure of scaffolds were identified by scanning electron microscopy and micro-computed tomography, which showed excellent fusion at the filament junctions, high uniformity, and complete interconnectivity of pore networks. The influences of process parameters on scaffolds' morphological and mechanical characteristics were studied. Data confirmed that the process parameters directly influenced the pore size, porosity, and, consequently, the mechanical properties of the scaffolds. The in vitro cell culture study was performed to investigate the influence of polymer nature and scaffold architecture on the adhesion of the cells onto the scaffolds using rabbit smooth muscle cells. Light, scanning electron, and confocal laser microscopy showed cell adhesion, proliferation, and extracellular matrix formation on the surface as well as inside the structure of both scaffold groups. The completely interconnected and highly regular honeycomb-like pore morphology supported bridging of the pores via cell-to-cell contact as well as production of extracellular matrix at later time points. The results indicated that the incorporation of hydrophilic PEG into hydrophobic PCL enhanced the overall hydrophilicity and cell culture performance of PCL-PEG copolymer. However, the scaffold architecture did not significantly influence the cell culture performance in this study." @default.
• W2045997611 created "2016-06-24" @default.
• W2045997611 creator A5003215109 @default.
• W2045997611 creator A5009983151 @default.
• W2045997611 creator A5052785778 @default.
• W2045997611 creator A5059021174 @default.
• W2045997611 creator A5063962991 @default.
• W2045997611 creator A5073994593 @default.
• W2045997611 creator A5084853754 @default.
• W2045997611 date "2009-10-01" @default.
• W2045997611 modified "2023-09-25" @default.
• W2045997611 title "Processing of Polycaprolactone and Polycaprolactone-Based Copolymers into 3D Scaffolds, and Their Cellular Responses" @default.
• W2045997611 cites W1571937934 @default.
• W2045997611 cites W1970467397 @default.
• W2045997611 cites W1970545663 @default.
• W2045997611 cites W1981259745 @default.
• W2045997611 cites W1984051675 @default.
• W2045997611 cites W1984589322 @default.
• W2045997611 cites W1984671834 @default.
• W2045997611 cites W2014006687 @default.
• W2045997611 cites W2015467025 @default.
• W2045997611 cites W2025852082 @default.
• W2045997611 cites W2032032896 @default.
• W2045997611 cites W2033594063 @default.
• W2045997611 cites W2035674015 @default.
• W2045997611 cites W2059815320 @default.
• W2045997611 cites W2064590369 @default.
• W2045997611 cites W2070963613 @default.
• W2045997611 cites W2072557182 @default.
• W2045997611 cites W2074639428 @default.
• W2045997611 cites W2075543804 @default.
• W2045997611 cites W2082135472 @default.
• W2045997611 cites W2087753698 @default.
• W2045997611 cites W2098901994 @default.
• W2045997611 cites W2103116614 @default.
• W2045997611 cites W2105130372 @default.
• W2045997611 cites W2122448541 @default.
• W2045997611 cites W2123633643 @default.
• W2045997611 cites W2124195334 @default.
• W2045997611 cites W2128767773 @default.
• W2045997611 cites W2165275748 @default.
• W2045997611 doi "https://doi.org/10.1089/ten.tea.2008.0355" @default.
• W2045997611 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19331580" @default.
• W2045997611 hasPublicationYear "2009" @default.
• W2045997611 type Work @default.
• W2045997611 sameAs 2045997611 @default.
• W2045997611 citedByCount "93" @default.
• W2045997611 countsByYear W20459976112012 @default.
• W2045997611 countsByYear W20459976112013 @default.
• W2045997611 countsByYear W20459976112014 @default.
• W2045997611 countsByYear W20459976112015 @default.
• W2045997611 countsByYear W20459976112016 @default.
• W2045997611 countsByYear W20459976112017 @default.
• W2045997611 countsByYear W20459976112018 @default.
• W2045997611 countsByYear W20459976112019 @default.
• W2045997611 countsByYear W20459976112020 @default.
• W2045997611 countsByYear W20459976112021 @default.
• W2045997611 countsByYear W20459976112022 @default.
• W2045997611 countsByYear W20459976112023 @default.
• W2045997611 crossrefType "journal-article" @default.
• W2045997611 hasAuthorship W2045997611A5003215109 @default.
• W2045997611 hasAuthorship W2045997611A5009983151 @default.
• W2045997611 hasAuthorship W2045997611A5052785778 @default.
• W2045997611 hasAuthorship W2045997611A5059021174 @default.
• W2045997611 hasAuthorship W2045997611A5063962991 @default.
• W2045997611 hasAuthorship W2045997611A5073994593 @default.
• W2045997611 hasAuthorship W2045997611A5084853754 @default.
• W2045997611 hasConcept C10138342 @default.
• W2045997611 hasConcept C127413603 @default.
• W2045997611 hasConcept C136229726 @default.
• W2045997611 hasConcept C154945302 @default.
• W2045997611 hasConcept C15920480 @default.
• W2045997611 hasConcept C159985019 @default.
• W2045997611 hasConcept C162324750 @default.
• W2045997611 hasConcept C185592680 @default.
• W2045997611 hasConcept C189165786 @default.
• W2045997611 hasConcept C192562407 @default.
• W2045997611 hasConcept C25516864 @default.
• W2045997611 hasConcept C26771246 @default.
• W2045997611 hasConcept C2779868350 @default.
• W2045997611 hasConcept C41008148 @default.
• W2045997611 hasConcept C42360764 @default.
• W2045997611 hasConcept C49892992 @default.
• W2045997611 hasConcept C521977710 @default.
• W2045997611 hasConcept C54400483 @default.
• W2045997611 hasConcept C55493867 @default.
• W2045997611 hasConcept C71924100 @default.
• W2045997611 hasConcept C84416704 @default.
• W2045997611 hasConcept C85789140 @default.
• W2045997611 hasConcept C89429830 @default.
• W2045997611 hasConceptScore W2045997611C10138342 @default.
• W2045997611 hasConceptScore W2045997611C127413603 @default.
• W2045997611 hasConceptScore W2045997611C136229726 @default.
• W2045997611 hasConceptScore W2045997611C154945302 @default.
• W2045997611 hasConceptScore W2045997611C15920480 @default.
• W2045997611 hasConceptScore W2045997611C159985019 @default.
• W2045997611 hasConceptScore W2045997611C162324750 @default.
• W2045997611 hasConceptScore W2045997611C185592680 @default.

• next