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- W2046088946 abstract "Abstract Summary: Synthesis, characteristics and medical diagnostic application of core‐shell poly(styrene/ α ‐ tert ‐butoxy‐ ω ‐(vinylbenzyl)polyglycidol) (P(S/PGL)) microspheres are described. The particles were prepared by soap‐free emulsion polymerization of styrene and α ‐ tert ‐butoxy‐ ω ‐(vinylbenzyl)polyglycidol macromonomer (PGL) initiated with potassium persulfate. The polymerization in water yielded microspheres with diameters in the range from 220 to 650 nm, depending on concentration of the macromonomer. Polydispersity was usually below 1.06. The fraction of PGL in interfacial layer of microspheres ranged from 0 to 42 mol.% (estimated by XPS). Microspheres suspended in NaCl solutions manifested fully reversible swelling‐deswelling properties of their interfacial layer with characteristic transition temperature ( T t ) slightly dependent on NaCl concentration. The adsorption of human serum albumin on the surface of P(S/PGL) microspheres was highly reduced when the PGL surface fraction exceeded 40 mol.%. P(S/PGL) microspheres with immobilized antigens Helicobacter pylori were used for detection of antibodies against. The test was based on monitoring differences in electrophoretic mobility of P(S/PGL) microspheres covalently bound H . pylori antigens and antibodies against H . pylori in blood serum." @default.
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- W2046088946 date "2009-07-01" @default.
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- W2046088946 title "Hydrophilic Microspheres Containing<i>αα</i>-<i>tert</i>Butoxy-<i>ωω</i>-vinylbenzyl-polyglycidol for Immunodiagnostics: Synthesis, Properties and Biomedical Applications" @default.
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- W2046088946 doi "https://doi.org/10.1002/masy.200950713" @default.
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