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- W2046099042 abstract "To determine the effect of interleukin 4 (IL-4) administration in a live sepsis model characterised by high-level production of tumour necrosis factor a (TNF-alpha), mice infected systemically with lethal or sublethal inocula of Pseudomonas aeruginosa were given the recombinant cytokine at different times before infection. Improved survival and decreased TNF-alpha production were observed in lethally infected mice treated with the cytokine 1 day before challenge. In contrast, increased mortality and overproduction of TNF-alpha were observed in sublethally infected mice given IL-4 at the time of infection." @default.
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- W2046099042 date "2000-04-01" @default.
- W2046099042 modified "2023-10-05" @default.
- W2046099042 title "DUAL EFFECT OF IL-4 ON RESISTANCE TO SYSTEMIC GRAM-NEGATIVE INFECTION AND PRODUCTION OF TNF-α" @default.
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- W2046099042 doi "https://doi.org/10.1006/cyto.1999.0576" @default.
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