Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046115598> ?p ?o ?g. }
- W2046115598 endingPage "4901" @default.
- W2046115598 startingPage "4895" @default.
- W2046115598 abstract "Interactions between salivary proline-rich proteins and tannins are involved in astringency, which is one of the most important organoleptic sensations perceived when drinking wine or tea. This work aimed to study interactions between a recombinant human salivary proline-rich protein, IB-5, and a flavan-3-ol monomer, epigallocatechin gallate (EGCG). IB-5 presented the characteristics of natively unfolded proteins. Interactions were studied by dynamic light scattering, isothermal titration microcalorimetry, and circular dichroism. The interaction mechanism was dependent on protein concentration. At low concentrations, a three-stage mechanism was evidenced. Saturation of the interaction sites (first stage) was followed by protein aggregation into metastable colloids at higher EGCG/protein ratios (second stage). Further increasing this ratio led to haze formation (third stage). At low ratios, a disorder-to-order transition of IB-5 structure upon binding was evidenced. At high protein concentrations, direct bridging between proteins and EGCG was observed, resulting in significantly lower aggregation and turbidity thresholds." @default.
- W2046115598 created "2016-06-24" @default.
- W2046115598 creator A5000653828 @default.
- W2046115598 creator A5010436375 @default.
- W2046115598 creator A5035483721 @default.
- W2046115598 creator A5042847264 @default.
- W2046115598 creator A5044080682 @default.
- W2046115598 creator A5072318876 @default.
- W2046115598 creator A5078183523 @default.
- W2046115598 date "2007-05-16" @default.
- W2046115598 modified "2023-10-14" @default.
- W2046115598 title "Interactions between a Non Glycosylated Human Proline-Rich Protein and Flavan-3-ols Are Affected by Protein Concentration and Polyphenol/Protein Ratio" @default.
- W2046115598 cites W1579664394 @default.
- W2046115598 cites W1720678970 @default.
- W2046115598 cites W1974810494 @default.
- W2046115598 cites W1980015132 @default.
- W2046115598 cites W1982476537 @default.
- W2046115598 cites W1990289617 @default.
- W2046115598 cites W2001004112 @default.
- W2046115598 cites W2001465291 @default.
- W2046115598 cites W2005817130 @default.
- W2046115598 cites W2016046529 @default.
- W2046115598 cites W2027211936 @default.
- W2046115598 cites W2037222355 @default.
- W2046115598 cites W2047820042 @default.
- W2046115598 cites W2052606462 @default.
- W2046115598 cites W2064251810 @default.
- W2046115598 cites W2075873814 @default.
- W2046115598 cites W2126548244 @default.
- W2046115598 cites W2132179389 @default.
- W2046115598 cites W2139852945 @default.
- W2046115598 cites W2149472608 @default.
- W2046115598 cites W2153681469 @default.
- W2046115598 cites W2167212038 @default.
- W2046115598 cites W2332461092 @default.
- W2046115598 doi "https://doi.org/10.1021/jf0704108" @default.
- W2046115598 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17503833" @default.
- W2046115598 hasPublicationYear "2007" @default.
- W2046115598 type Work @default.
- W2046115598 sameAs 2046115598 @default.
- W2046115598 citedByCount "125" @default.
- W2046115598 countsByYear W20461155982012 @default.
- W2046115598 countsByYear W20461155982013 @default.
- W2046115598 countsByYear W20461155982014 @default.
- W2046115598 countsByYear W20461155982015 @default.
- W2046115598 countsByYear W20461155982016 @default.
- W2046115598 countsByYear W20461155982017 @default.
- W2046115598 countsByYear W20461155982018 @default.
- W2046115598 countsByYear W20461155982019 @default.
- W2046115598 countsByYear W20461155982020 @default.
- W2046115598 countsByYear W20461155982021 @default.
- W2046115598 countsByYear W20461155982022 @default.
- W2046115598 countsByYear W20461155982023 @default.
- W2046115598 crossrefType "journal-article" @default.
- W2046115598 hasAuthorship W2046115598A5000653828 @default.
- W2046115598 hasAuthorship W2046115598A5010436375 @default.
- W2046115598 hasAuthorship W2046115598A5035483721 @default.
- W2046115598 hasAuthorship W2046115598A5042847264 @default.
- W2046115598 hasAuthorship W2046115598A5044080682 @default.
- W2046115598 hasAuthorship W2046115598A5072318876 @default.
- W2046115598 hasAuthorship W2046115598A5078183523 @default.
- W2046115598 hasConcept C11804247 @default.
- W2046115598 hasConcept C121332964 @default.
- W2046115598 hasConcept C12554922 @default.
- W2046115598 hasConcept C133571119 @default.
- W2046115598 hasConcept C136238340 @default.
- W2046115598 hasConcept C156911925 @default.
- W2046115598 hasConcept C185592680 @default.
- W2046115598 hasConcept C2777192995 @default.
- W2046115598 hasConcept C2778004101 @default.
- W2046115598 hasConcept C2779815552 @default.
- W2046115598 hasConcept C31903555 @default.
- W2046115598 hasConcept C3288061 @default.
- W2046115598 hasConcept C43617362 @default.
- W2046115598 hasConcept C45902088 @default.
- W2046115598 hasConcept C47701112 @default.
- W2046115598 hasConcept C515207424 @default.
- W2046115598 hasConcept C55493867 @default.
- W2046115598 hasConcept C62520636 @default.
- W2046115598 hasConcept C70899900 @default.
- W2046115598 hasConcept C77784730 @default.
- W2046115598 hasConcept C86803240 @default.
- W2046115598 hasConceptScore W2046115598C11804247 @default.
- W2046115598 hasConceptScore W2046115598C121332964 @default.
- W2046115598 hasConceptScore W2046115598C12554922 @default.
- W2046115598 hasConceptScore W2046115598C133571119 @default.
- W2046115598 hasConceptScore W2046115598C136238340 @default.
- W2046115598 hasConceptScore W2046115598C156911925 @default.
- W2046115598 hasConceptScore W2046115598C185592680 @default.
- W2046115598 hasConceptScore W2046115598C2777192995 @default.
- W2046115598 hasConceptScore W2046115598C2778004101 @default.
- W2046115598 hasConceptScore W2046115598C2779815552 @default.
- W2046115598 hasConceptScore W2046115598C31903555 @default.
- W2046115598 hasConceptScore W2046115598C3288061 @default.
- W2046115598 hasConceptScore W2046115598C43617362 @default.
- W2046115598 hasConceptScore W2046115598C45902088 @default.
- W2046115598 hasConceptScore W2046115598C47701112 @default.
- W2046115598 hasConceptScore W2046115598C515207424 @default.