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- W204611972 abstract "The only phospholipid containing structure in mammalian erythrocytes is the plasma membrane. The matrix of this membrane is formed by a lipid bi- layer in which four major phospholipid classes are arranged. Their polar headgroups border the water phase and their acyl chains extend into the inner part of the bilayer, which, therefore, has an apolar character. Cholesterol, being present in a nearly 1:1 ratio to phospholipid, imposes an intermediate fluid state onto the phospholipids, allowing a rapid diffusion of the lipid molecules in the plane of the membrane. Embedded in this fluid lipid film are proteins that either freely float in the plane of the bilayer or are restricted in their mobility by an interaction with proteins at the inside or on the outside of the membrane. The intrinsic proteins and, therefore, a number of functions are asymmetrically arranged in the bilayer. The specific interactions of these proteins with certain phospholipid classes and also the difference in physico-chemical properties of the four major phospholipids suggest a defined asymmetric arrangement for the phospholipids as well." @default.
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- W204611972 date "1981-01-01" @default.
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- W204611972 title "ARRANGEMENT AND DYNAMICS OF PHOSPHOLIPIDS IN MAMMALIAN ERYTHROCYTES" @default.
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- W204611972 doi "https://doi.org/10.1016/b978-0-08-026818-7.50034-8" @default.
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