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- W2046139196 abstract "Background: The ambulatory arterial stiffness index (AASI) is a new index that reflects the dynamic relation between diastolic and systolic blood pressure though the circadian blood pressure rhythm. The purpose of this study was to investigate the association between AASI, dipping status and pulse pressure as a index of arterial stiffness in normotensive adolescents. Methods: This was a cross-sectional study conducted with 253 high school students (115 boys and 138 girls), aged between 12 to 18 years (14.89 ± 1.7). A 24 hours ambulatory blood pressure monitoring was carried out to all patients using a Spacelabs monitor. Normal dipping was defined as a > or equal 10% decline in mean systolic and diastolic ambulatory blood pressure from day to night. We determined the diurnal and nocturnal blood pressure and brachial pulse pressure values and computed AASI for each participant. Results: AASI was a strong predictor for systolic and diastolic nocturnal blood pressure fall (r = −0.369 and −0.305, respectively; P < 0.0001). No gender difference was apparent for these characteristics. Additionaly, AASI predicted the status of dipping/nondipping (P = 0.002). Nondippers showed significantly higher AASI than dippers (0.407 ± 0.17 vs. 0.295 ± 0.13; P < 0.0001). However, dipper and nondipper conditions were not affected the association between AASI and brachial pulse pressure (r = 0.176; P = 0.005). Conclusion: AASI is strongly correlated with nocturnal blood pressure fall and is increased in nondipping. Additionallly, we show that the association between brachial pulse as indicator of arterial stiffness and AASI is independent of the characterization of the dipping or notdipping status in normotensive adolescents." @default.
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- W2046139196 date "2010-06-01" @default.
- W2046139196 modified "2023-09-27" @default.
- W2046139196 title "AMBULATORY ARTERIAL STIFFNESS INDEX AND BRACHIAL PULSE PRESSURE: THE INFLUENCE OF CIRCADIAN BLOOD PRESSURE RHYTHM IN NORMOTENSIVE ADOLESCENTS: PP.3.114" @default.
- W2046139196 doi "https://doi.org/10.1097/01.hjh.0000378438.70563.e8" @default.
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