Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046166687> ?p ?o ?g. }
- W2046166687 endingPage "433" @default.
- W2046166687 startingPage "428" @default.
- W2046166687 abstract "Studies on dendritic cells (DC) of the respiratory and gastric mucosae have identified an extensive network of cells that represent the predominant antigen-presenting cell type at these sites. Under steady-state conditions, respiratory tract DC (RTDC) are specialized for antigen uptake and spontaneously migrate to local lymph nodes, although in vivo transfer studies have shown that the T-cell priming activity of these cells is restricted to low-level, Th2-skewed responses. Following exposure to inflammatory stimuli, the migration of RTDC to lymph nodes is accelerated and is associated with a rapid and dramatic increase in the ability of these cells to induce both Th1- and Th2-dependent immunity. Under normal circumstances, however, responsiveness of epithelial RTDC to maturation stimuli is regulated by locally produced micro-environmental factors, including pro-inflammatory cytokines, reactive oxygen species and prostanoids. These studies have led to a greater understanding of airway DC function and their role in T helper cell differentiation and provide the basis for future studies to determine the role of the cells in the aetiology and pathogenesis of respiratory immunoinflammatory disorders." @default.
- W2046166687 created "2016-06-24" @default.
- W2046166687 creator A5011128959 @default.
- W2046166687 date "1999-10-01" @default.
- W2046166687 modified "2023-10-06" @default.
- W2046166687 title "Regulation of T helper cell differentiation by respiratory tract dendritic cells" @default.
- W2046166687 cites W1568945049 @default.
- W2046166687 cites W1571356298 @default.
- W2046166687 cites W1572210960 @default.
- W2046166687 cites W1578157386 @default.
- W2046166687 cites W1609713897 @default.
- W2046166687 cites W1656256413 @default.
- W2046166687 cites W1675056235 @default.
- W2046166687 cites W1888921446 @default.
- W2046166687 cites W1902157155 @default.
- W2046166687 cites W1957825789 @default.
- W2046166687 cites W1972306920 @default.
- W2046166687 cites W1981178699 @default.
- W2046166687 cites W1983094057 @default.
- W2046166687 cites W1990174772 @default.
- W2046166687 cites W1994263397 @default.
- W2046166687 cites W2002122771 @default.
- W2046166687 cites W2035572849 @default.
- W2046166687 cites W2035580952 @default.
- W2046166687 cites W2046954690 @default.
- W2046166687 cites W2051412420 @default.
- W2046166687 cites W2054930447 @default.
- W2046166687 cites W2062298433 @default.
- W2046166687 cites W2075505444 @default.
- W2046166687 cites W2077654197 @default.
- W2046166687 cites W2086592423 @default.
- W2046166687 cites W2090202304 @default.
- W2046166687 cites W2095016279 @default.
- W2046166687 cites W2097682908 @default.
- W2046166687 cites W2099149994 @default.
- W2046166687 cites W2099450563 @default.
- W2046166687 cites W2107954314 @default.
- W2046166687 cites W2114308840 @default.
- W2046166687 cites W2115784025 @default.
- W2046166687 cites W2116716017 @default.
- W2046166687 cites W2117477141 @default.
- W2046166687 cites W2123079517 @default.
- W2046166687 cites W2123190790 @default.
- W2046166687 cites W2134934993 @default.
- W2046166687 cites W2140117437 @default.
- W2046166687 cites W2140944306 @default.
- W2046166687 cites W2141523423 @default.
- W2046166687 cites W2146240100 @default.
- W2046166687 cites W2150564865 @default.
- W2046166687 cites W2161362125 @default.
- W2046166687 cites W2163682172 @default.
- W2046166687 cites W2177327503 @default.
- W2046166687 cites W2322403437 @default.
- W2046166687 cites W2322825986 @default.
- W2046166687 doi "https://doi.org/10.1046/j.1440-1711.1999.00850.x" @default.
- W2046166687 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10540209" @default.
- W2046166687 hasPublicationYear "1999" @default.
- W2046166687 type Work @default.
- W2046166687 sameAs 2046166687 @default.
- W2046166687 citedByCount "22" @default.
- W2046166687 countsByYear W20461666872014 @default.
- W2046166687 countsByYear W20461666872017 @default.
- W2046166687 countsByYear W20461666872023 @default.
- W2046166687 crossrefType "journal-article" @default.
- W2046166687 hasAuthorship W2046166687A5011128959 @default.
- W2046166687 hasConcept C100701293 @default.
- W2046166687 hasConcept C104317684 @default.
- W2046166687 hasConcept C105702510 @default.
- W2046166687 hasConcept C142724271 @default.
- W2046166687 hasConcept C147483822 @default.
- W2046166687 hasConcept C148738053 @default.
- W2046166687 hasConcept C154317977 @default.
- W2046166687 hasConcept C202751555 @default.
- W2046166687 hasConcept C203014093 @default.
- W2046166687 hasConcept C2776090121 @default.
- W2046166687 hasConcept C2778170410 @default.
- W2046166687 hasConcept C2779644171 @default.
- W2046166687 hasConcept C2779720271 @default.
- W2046166687 hasConcept C39347974 @default.
- W2046166687 hasConcept C534529494 @default.
- W2046166687 hasConcept C55493867 @default.
- W2046166687 hasConcept C59822182 @default.
- W2046166687 hasConcept C67662055 @default.
- W2046166687 hasConcept C71924100 @default.
- W2046166687 hasConcept C81444415 @default.
- W2046166687 hasConcept C86803240 @default.
- W2046166687 hasConcept C8891405 @default.
- W2046166687 hasConcept C90375314 @default.
- W2046166687 hasConcept C95444343 @default.
- W2046166687 hasConceptScore W2046166687C100701293 @default.
- W2046166687 hasConceptScore W2046166687C104317684 @default.
- W2046166687 hasConceptScore W2046166687C105702510 @default.
- W2046166687 hasConceptScore W2046166687C142724271 @default.
- W2046166687 hasConceptScore W2046166687C147483822 @default.
- W2046166687 hasConceptScore W2046166687C148738053 @default.
- W2046166687 hasConceptScore W2046166687C154317977 @default.
- W2046166687 hasConceptScore W2046166687C202751555 @default.
- W2046166687 hasConceptScore W2046166687C203014093 @default.