Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046168051> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2046168051 endingPage "730" @default.
- W2046168051 startingPage "726" @default.
- W2046168051 abstract "To examine gap junction expression during compensatory renal growth. Compensatory renal growth is a normal response to the removal of renal cells. Gap junctional intercellular communication plays important roles in homeostatic regulation, differentiation, and synchronization of cellular electronic and metabolic functions.The right ureters of 5-week-old ddy mice were dorsally incised and unilaterally obstructed, and the animals were killed at varying intervals. The control group underwent a sham operation. Freeze-fractured kidney tissue samples were studied using electron microscopy. The amount of proliferative cell nuclear antigen-positive cells and connexin 43 (Cx43) protein was studied by immunohistochemistry and Western blotting, respectively.Proliferative cell nuclear antigen-positive cells in the renal tubules increased on days 1 and 2 after surgery that obstructed the ureter, and decreased to normal levels by day 14. The number of gap junctions significantly decreased on days 1 and 2, and then gradually increased to normal levels from days 3 to 14 after surgery. The amount of Cx43 protein in the renal tubules decreased until day 2 and recovered to the same level as that of the control by day 14 after surgery. Significantly, a hyperphosphorylated band of Cx43 in the control kidney was not detected in the operated kidney.These data suggest that the gap junctional intercellular communication of renal tubular cells during compensatory renal growth after unilateral ureteral obstruction could be temporarily reduced concomitant with a decrease of the expression of a phosphorylated Cx43 protein in renal cortical tubular cells after unilateral ureteral obstruction of the contralateral kidney." @default.
- W2046168051 created "2016-06-24" @default.
- W2046168051 creator A5006648466 @default.
- W2046168051 creator A5043058133 @default.
- W2046168051 creator A5063725245 @default.
- W2046168051 creator A5069385514 @default.
- W2046168051 creator A5070459900 @default.
- W2046168051 creator A5090538257 @default.
- W2046168051 date "2002-10-01" @default.
- W2046168051 modified "2023-09-24" @default.
- W2046168051 title "Transient decrease in gap junction expression during compensatory renal growth in mice" @default.
- W2046168051 cites W1977903246 @default.
- W2046168051 cites W1988316236 @default.
- W2046168051 cites W1992919597 @default.
- W2046168051 cites W2000803261 @default.
- W2046168051 cites W2005970270 @default.
- W2046168051 cites W2008487276 @default.
- W2046168051 cites W2034357696 @default.
- W2046168051 cites W2038254522 @default.
- W2046168051 cites W2045345274 @default.
- W2046168051 cites W2069035576 @default.
- W2046168051 cites W2090103994 @default.
- W2046168051 cites W2091360853 @default.
- W2046168051 cites W2093843907 @default.
- W2046168051 cites W2099041122 @default.
- W2046168051 cites W2151101974 @default.
- W2046168051 doi "https://doi.org/10.1016/s0090-4295(02)01837-x" @default.
- W2046168051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12385951" @default.
- W2046168051 hasPublicationYear "2002" @default.
- W2046168051 type Work @default.
- W2046168051 sameAs 2046168051 @default.
- W2046168051 citedByCount "5" @default.
- W2046168051 crossrefType "journal-article" @default.
- W2046168051 hasAuthorship W2046168051A5006648466 @default.
- W2046168051 hasAuthorship W2046168051A5043058133 @default.
- W2046168051 hasAuthorship W2046168051A5063725245 @default.
- W2046168051 hasAuthorship W2046168051A5069385514 @default.
- W2046168051 hasAuthorship W2046168051A5070459900 @default.
- W2046168051 hasAuthorship W2046168051A5090538257 @default.
- W2046168051 hasConcept C104317684 @default.
- W2046168051 hasConcept C126322002 @default.
- W2046168051 hasConcept C134018914 @default.
- W2046168051 hasConcept C142724271 @default.
- W2046168051 hasConcept C158157758 @default.
- W2046168051 hasConcept C204232928 @default.
- W2046168051 hasConcept C2780091579 @default.
- W2046168051 hasConcept C2780228694 @default.
- W2046168051 hasConcept C54355233 @default.
- W2046168051 hasConcept C55493867 @default.
- W2046168051 hasConcept C62112901 @default.
- W2046168051 hasConcept C71924100 @default.
- W2046168051 hasConcept C79879829 @default.
- W2046168051 hasConcept C85265743 @default.
- W2046168051 hasConcept C86803240 @default.
- W2046168051 hasConcept C95444343 @default.
- W2046168051 hasConceptScore W2046168051C104317684 @default.
- W2046168051 hasConceptScore W2046168051C126322002 @default.
- W2046168051 hasConceptScore W2046168051C134018914 @default.
- W2046168051 hasConceptScore W2046168051C142724271 @default.
- W2046168051 hasConceptScore W2046168051C158157758 @default.
- W2046168051 hasConceptScore W2046168051C204232928 @default.
- W2046168051 hasConceptScore W2046168051C2780091579 @default.
- W2046168051 hasConceptScore W2046168051C2780228694 @default.
- W2046168051 hasConceptScore W2046168051C54355233 @default.
- W2046168051 hasConceptScore W2046168051C55493867 @default.
- W2046168051 hasConceptScore W2046168051C62112901 @default.
- W2046168051 hasConceptScore W2046168051C71924100 @default.
- W2046168051 hasConceptScore W2046168051C79879829 @default.
- W2046168051 hasConceptScore W2046168051C85265743 @default.
- W2046168051 hasConceptScore W2046168051C86803240 @default.
- W2046168051 hasConceptScore W2046168051C95444343 @default.
- W2046168051 hasFunder F4320320912 @default.
- W2046168051 hasIssue "4" @default.
- W2046168051 hasLocation W20461680511 @default.
- W2046168051 hasLocation W20461680512 @default.
- W2046168051 hasOpenAccess W2046168051 @default.
- W2046168051 hasPrimaryLocation W20461680511 @default.
- W2046168051 hasRelatedWork W1991564557 @default.
- W2046168051 hasRelatedWork W2028295576 @default.
- W2046168051 hasRelatedWork W2107376191 @default.
- W2046168051 hasRelatedWork W2119338320 @default.
- W2046168051 hasRelatedWork W2119426718 @default.
- W2046168051 hasRelatedWork W2123361718 @default.
- W2046168051 hasRelatedWork W2366943750 @default.
- W2046168051 hasRelatedWork W2368900963 @default.
- W2046168051 hasRelatedWork W2606018528 @default.
- W2046168051 hasRelatedWork W2920933529 @default.
- W2046168051 hasVolume "60" @default.
- W2046168051 isParatext "false" @default.
- W2046168051 isRetracted "false" @default.
- W2046168051 magId "2046168051" @default.
- W2046168051 workType "article" @default.