FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046177612> ?p ?o ?g. }

• W2046177612 endingPage "403" @default.
• W2046177612 startingPage "399" @default.
• W2046177612 abstract "Obstructive sleep apnea is a prevalent disorder associated with significant neurobehavioral and cardiovascular morbidities. At present, however, there are no widely effective, well-tolerated pharmacotherapies for obstructive sleep apnea. The pathogenesis of this disorder predicts that sleep apnea should respond to drug therapies. Specifically, respiration during waking in persons with sleep apnea is normal, while collapse of the upper airway occurs exclusively in sleep. This state-dependency in upper airway patency suggests state-dependent changes in neurochemical control of the upper airway dilator motoneurons, and this, in turn, suggests that appropriate medications would maintain upper airway dilator function in sleep and prevent sleep related collapse of the upper airway. The past few years have brought significant insight into the neural mechanisms governing upper airway dilator muscle function. This article provides updates on neurochemical mechanisms, emphasizing a role for serotonergic control, and reviews recent drug therapy trials for sleep apnea. We are currently well poised to develop effective pharmacotherapies for obstructive sleep apnea, with opportunities to target several regions involved in respiratory control." @default.
• W2046177612 created "2016-06-24" @default.
• W2046177612 creator A5022164053 @default.
• W2046177612 date "2001-11-01" @default.
• W2046177612 modified "2023-09-26" @default.
• W2046177612 title "Pharmacotherapies for obstructive sleep apnea: how close are we?" @default.
• W2046177612 cites W1972862048 @default.
• W2046177612 cites W1978368760 @default.
• W2046177612 cites W2010048767 @default.
• W2046177612 cites W2027210685 @default.
• W2046177612 cites W2035196242 @default.
• W2046177612 cites W2035771827 @default.
• W2046177612 cites W2036208132 @default.
• W2046177612 cites W2037109893 @default.
• W2046177612 cites W2050244432 @default.
• W2046177612 cites W2056586945 @default.
• W2046177612 cites W2057060520 @default.
• W2046177612 cites W2068574939 @default.
• W2046177612 cites W2070866648 @default.
• W2046177612 cites W2073056023 @default.
• W2046177612 cites W2077904893 @default.
• W2046177612 cites W2092477257 @default.
• W2046177612 cites W2106403392 @default.
• W2046177612 cites W2114429795 @default.
• W2046177612 cites W2131678043 @default.
• W2046177612 cites W2139404323 @default.
• W2046177612 cites W2163944618 @default.
• W2046177612 cites W2217947520 @default.
• W2046177612 cites W2333343699 @default.
• W2046177612 cites W2395135404 @default.
• W2046177612 cites W2785563066 @default.
• W2046177612 doi "https://doi.org/10.1097/00063198-200111000-00006" @default.
• W2046177612 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11706315" @default.
• W2046177612 hasPublicationYear "2001" @default.
• W2046177612 type Work @default.
• W2046177612 sameAs 2046177612 @default.
• W2046177612 citedByCount "31" @default.
• W2046177612 countsByYear W20461776122012 @default.
• W2046177612 countsByYear W20461776122014 @default.
• W2046177612 countsByYear W20461776122015 @default.
• W2046177612 countsByYear W20461776122017 @default.
• W2046177612 crossrefType "journal-article" @default.
• W2046177612 hasAuthorship W2046177612A5022164053 @default.
• W2046177612 hasConcept C105922876 @default.
• W2046177612 hasConcept C111919701 @default.
• W2046177612 hasConcept C118552586 @default.
• W2046177612 hasConcept C126322002 @default.
• W2046177612 hasConcept C1513209611 @default.
• W2046177612 hasConcept C170493617 @default.
• W2046177612 hasConcept C25876315 @default.
• W2046177612 hasConcept C2775841894 @default.
• W2046177612 hasConcept C2775864247 @default.
• W2046177612 hasConcept C2776006263 @default.
• W2046177612 hasConcept C2777032099 @default.
• W2046177612 hasConcept C2777935920 @default.
• W2046177612 hasConcept C2778205975 @default.
• W2046177612 hasConcept C2780168309 @default.
• W2046177612 hasConcept C2781210498 @default.
• W2046177612 hasConcept C2781326671 @default.
• W2046177612 hasConcept C37000724 @default.
• W2046177612 hasConcept C41008148 @default.
• W2046177612 hasConcept C42219234 @default.
• W2046177612 hasConcept C71924100 @default.
• W2046177612 hasConceptScore W2046177612C105922876 @default.
• W2046177612 hasConceptScore W2046177612C111919701 @default.
• W2046177612 hasConceptScore W2046177612C118552586 @default.
• W2046177612 hasConceptScore W2046177612C126322002 @default.
• W2046177612 hasConceptScore W2046177612C1513209611 @default.
• W2046177612 hasConceptScore W2046177612C170493617 @default.
• W2046177612 hasConceptScore W2046177612C25876315 @default.
• W2046177612 hasConceptScore W2046177612C2775841894 @default.
• W2046177612 hasConceptScore W2046177612C2775864247 @default.
• W2046177612 hasConceptScore W2046177612C2776006263 @default.
• W2046177612 hasConceptScore W2046177612C2777032099 @default.
• W2046177612 hasConceptScore W2046177612C2777935920 @default.
• W2046177612 hasConceptScore W2046177612C2778205975 @default.
• W2046177612 hasConceptScore W2046177612C2780168309 @default.
• W2046177612 hasConceptScore W2046177612C2781210498 @default.
• W2046177612 hasConceptScore W2046177612C2781326671 @default.
• W2046177612 hasConceptScore W2046177612C37000724 @default.
• W2046177612 hasConceptScore W2046177612C41008148 @default.
• W2046177612 hasConceptScore W2046177612C42219234 @default.
• W2046177612 hasConceptScore W2046177612C71924100 @default.
• W2046177612 hasIssue "6" @default.
• W2046177612 hasLocation W20461776121 @default.
• W2046177612 hasLocation W20461776122 @default.
• W2046177612 hasOpenAccess W2046177612 @default.
• W2046177612 hasPrimaryLocation W20461776121 @default.
• W2046177612 hasRelatedWork W2029630499 @default.
• W2046177612 hasRelatedWork W2140876245 @default.
• W2046177612 hasRelatedWork W2158022034 @default.
• W2046177612 hasRelatedWork W2399849466 @default.
• W2046177612 hasRelatedWork W2412780993 @default.
• W2046177612 hasRelatedWork W2989426537 @default.
• W2046177612 hasRelatedWork W3163140084 @default.
• W2046177612 hasRelatedWork W4280629295 @default.
• W2046177612 hasRelatedWork W4295775062 @default.
• W2046177612 hasRelatedWork W4382599652 @default.

• next