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- W2046187811 abstract "Bisphosphonate medications are potent inhibitors of osteoclast-mediated bone resorption that have an important role to play in the management of many patients. Intravenous bisphosphonate medications are effective in preventing and reducing hypercalcemia, stabilizing benign and malignant bony pathology, and preventing fractures (skeletal related events) of bones infiltrated by malignant disease. As such, the use of zoledronic acid (Zometa) has become widely and routinely used in the treatment of many patients facing these problems. Newer indications for intravenous bisphosphonate medications include its use in refractory osteoporosis. Finally, recent observations identify the effectiveness of Zometa in the treatment of breast cancer. Oral bisphosphonates are approved to treat osteoporosis and are frequently utilized in the treatment of osteopenia, as well. While these indications are the most common for the administration of oral bisphosphonates, their use in the treatment of Paget's disease and osteogenesis imperfecta has been described, and the use of bisphosphonate medications in the management of giant cell lesions of the jaws has also been recommended. No doubt, the quality, and often the length of life, is enhanced in patients treated with bisphosphonate medications." @default.
- W2046187811 created "2016-06-24" @default.
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- W2046187811 date "2009-09-01" @default.
- W2046187811 modified "2023-09-25" @default.
- W2046187811 title "L512: Bisphosphonate-Related Osteonecrosis of the Jaws" @default.
- W2046187811 cites W1990119475 @default.
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- W2046187811 doi "https://doi.org/10.1016/j.joms.2009.05.275" @default.
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