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- W2046194150 abstract "Significance Microbes commonly form dense communities that are central to many diseases and bioremediation. Here we demonstrate a simple and general principle of living in dense communities: microbes will commonly compete to reach nutrients at the community edge, akin to plants competing for light. We follow the evolution of a highly competitive genotype in colonies of a soil bacterium. We show that the genotype gains its advantage not from its intrinsic growth rate but by positioning itself at the surface of the community, where it gains preferential access to oxygen. A large-scale genetic analysis reveals striking parallel evolution and evidence of strong natural selection. Our work suggests that positioning is a major basis for evolutionary competition in dense microbial communities." @default.
- W2046194150 created "2016-06-24" @default.
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- W2046194150 date "2014-04-08" @default.
- W2046194150 modified "2023-10-11" @default.
- W2046194150 title "Importance of positioning for microbial evolution" @default.
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- W2046194150 doi "https://doi.org/10.1073/pnas.1323632111" @default.
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