Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046200123> ?p ?o ?g. }
- W2046200123 endingPage "966" @default.
- W2046200123 startingPage "962" @default.
- W2046200123 abstract "Aged garlic extract (AGE) has recently received attention as a potent anti-fatigue agent. The principal aim of this study was to elucidate the mechanism responsible for the ameliorating effect of AGE on physical fatigue in rats caused by repeated endurance exercise on a mechanical treadmill apparatus. Rats were subjected to endurance exercise 5 times per week for 4 weeks. AGE at a dosage of 2.86 g/kg was administrated to rats 30 min before every exercise. Succinate dehydrogenase (SDH) activity in the gastrocnemius and soleus muscles and superoxide dismutase (SOD) activity, nitric oxide (NO) metabolites, and lactic acid concentration in plasma were evaluated as biomarkers of physical fatigue. SDH activity was increased 2—4-fold by repeated endurance exercise in comparison with unexercised (intact) rats, and AGE further up-regulated this activity by 40%. SOD activity was increased 5-fold, whereas AGE maintained it at a level equivalent to that in intact rats. Levels of NO metabolites were slightly decreased, whereas AGE enhanced them 2-fold. Lactic acid concentration was not changed in any of the groups. These results indicate that AGE may facilitate the turnover of aerobic glucose metabolism, attenuate oxidative stress, and promote oxygen supply based on vasodilation, suggesting that AGE ameliorates the various impairments associated with physical fatigue." @default.
- W2046200123 created "2016-06-24" @default.
- W2046200123 creator A5004995074 @default.
- W2046200123 creator A5012165905 @default.
- W2046200123 creator A5017312910 @default.
- W2046200123 creator A5029028314 @default.
- W2046200123 creator A5042473369 @default.
- W2046200123 creator A5060157290 @default.
- W2046200123 creator A5072842756 @default.
- W2046200123 date "2006-01-01" @default.
- W2046200123 modified "2023-09-29" @default.
- W2046200123 title "Aged Garlic Extract Ameliorates Physical Fatigue" @default.
- W2046200123 cites W1544423740 @default.
- W2046200123 cites W1584415349 @default.
- W2046200123 cites W1615913434 @default.
- W2046200123 cites W1775749144 @default.
- W2046200123 cites W1821918060 @default.
- W2046200123 cites W1965731970 @default.
- W2046200123 cites W1970096029 @default.
- W2046200123 cites W1976824480 @default.
- W2046200123 cites W1995560440 @default.
- W2046200123 cites W2000882478 @default.
- W2046200123 cites W2015756895 @default.
- W2046200123 cites W2019385148 @default.
- W2046200123 cites W2039807797 @default.
- W2046200123 cites W2046360254 @default.
- W2046200123 cites W2047038879 @default.
- W2046200123 cites W2048778050 @default.
- W2046200123 cites W2052603573 @default.
- W2046200123 cites W2058164136 @default.
- W2046200123 cites W2068949535 @default.
- W2046200123 cites W2069438539 @default.
- W2046200123 cites W2072300234 @default.
- W2046200123 cites W2083501616 @default.
- W2046200123 cites W2094232844 @default.
- W2046200123 cites W2095417952 @default.
- W2046200123 cites W2103854085 @default.
- W2046200123 cites W2115153703 @default.
- W2046200123 cites W2134831942 @default.
- W2046200123 cites W2156909950 @default.
- W2046200123 cites W2170423033 @default.
- W2046200123 cites W2325704884 @default.
- W2046200123 cites W2428825111 @default.
- W2046200123 cites W4230212703 @default.
- W2046200123 cites W4251493674 @default.
- W2046200123 cites W4256518021 @default.
- W2046200123 doi "https://doi.org/10.1248/bpb.29.962" @default.
- W2046200123 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16651727" @default.
- W2046200123 hasPublicationYear "2006" @default.
- W2046200123 type Work @default.
- W2046200123 sameAs 2046200123 @default.
- W2046200123 citedByCount "56" @default.
- W2046200123 countsByYear W20462001232012 @default.
- W2046200123 countsByYear W20462001232013 @default.
- W2046200123 countsByYear W20462001232014 @default.
- W2046200123 countsByYear W20462001232015 @default.
- W2046200123 countsByYear W20462001232016 @default.
- W2046200123 countsByYear W20462001232017 @default.
- W2046200123 countsByYear W20462001232018 @default.
- W2046200123 countsByYear W20462001232019 @default.
- W2046200123 countsByYear W20462001232020 @default.
- W2046200123 countsByYear W20462001232021 @default.
- W2046200123 countsByYear W20462001232023 @default.
- W2046200123 crossrefType "journal-article" @default.
- W2046200123 hasAuthorship W2046200123A5004995074 @default.
- W2046200123 hasAuthorship W2046200123A5012165905 @default.
- W2046200123 hasAuthorship W2046200123A5017312910 @default.
- W2046200123 hasAuthorship W2046200123A5029028314 @default.
- W2046200123 hasAuthorship W2046200123A5042473369 @default.
- W2046200123 hasAuthorship W2046200123A5060157290 @default.
- W2046200123 hasAuthorship W2046200123A5072842756 @default.
- W2046200123 hasBestOaLocation W20462001231 @default.
- W2046200123 hasConcept C103038586 @default.
- W2046200123 hasConcept C126322002 @default.
- W2046200123 hasConcept C134018914 @default.
- W2046200123 hasConcept C181588539 @default.
- W2046200123 hasConcept C185592680 @default.
- W2046200123 hasConcept C2775838275 @default.
- W2046200123 hasConcept C2775920511 @default.
- W2046200123 hasConcept C2776151105 @default.
- W2046200123 hasConcept C2781464450 @default.
- W2046200123 hasConcept C519581460 @default.
- W2046200123 hasConcept C523546767 @default.
- W2046200123 hasConcept C54355233 @default.
- W2046200123 hasConcept C71924100 @default.
- W2046200123 hasConcept C86803240 @default.
- W2046200123 hasConcept C99830354 @default.
- W2046200123 hasConceptScore W2046200123C103038586 @default.
- W2046200123 hasConceptScore W2046200123C126322002 @default.
- W2046200123 hasConceptScore W2046200123C134018914 @default.
- W2046200123 hasConceptScore W2046200123C181588539 @default.
- W2046200123 hasConceptScore W2046200123C185592680 @default.
- W2046200123 hasConceptScore W2046200123C2775838275 @default.
- W2046200123 hasConceptScore W2046200123C2775920511 @default.
- W2046200123 hasConceptScore W2046200123C2776151105 @default.
- W2046200123 hasConceptScore W2046200123C2781464450 @default.
- W2046200123 hasConceptScore W2046200123C519581460 @default.
- W2046200123 hasConceptScore W2046200123C523546767 @default.