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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046202236> ?p ?o ?g. }

• W2046202236 endingPage "5306" @default.
• W2046202236 startingPage "5302" @default.
• W2046202236 abstract "Dual inhibitors of bacterial gyrB and parE based on a 5-(2-pyrimidinyl)-imidazo[1,2-a]pyridine template exhibited MICs (microg/mL) of 0.06-64 (Sau), 0.25-64 (MRSA), 0.06-64 (Spy), 0.06-64 (Spn), and 0.03-64 (FQR Spn). Selected examples were efficacious in mouse sepsis and lung infection models at <50mg/kg (PO dosing)." @default.
• W2046202236 created "2016-06-24" @default.
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• W2046202236 date "2009-09-01" @default.
• W2046202236 modified "2023-10-18" @default.
• W2046202236 title "5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV" @default.
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• W2046202236 doi "https://doi.org/10.1016/j.bmcl.2009.07.141" @default.
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