FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046205923> ?p ?o ?g. }

• W2046205923 endingPage "ons282" @default.
• W2046205923 startingPage "ons277" @default.
• W2046205923 abstract "In Brief BACKGROUND Treating deep-seated cerebral lesions often requires retracting the brain. Retraction, however, causes clinically significant postoperative neurological deficits in 3% to 9% of intracranial cases. OBJECTIVE This pilot study used automated analysis of postoperative magnetic resonance images (MRIs) to determine whether brain retraction caused local anatomic changes to the cerebral neocortex and whether such changes represented sensitive markers for detecting brain retraction injury. METHODS Pre- and postoperative maps of whole-brain cortical thickness were generated from 3-dimensional MRIs of 6 patients who underwent selective amygdalohippocampectomy for temporal lobe epilepsy (5 left hemispheres, 1 right hemisphere). Mean cortical thickness was determined in the inferior temporal gyrus (ITG test), where a retractor was placed during surgery, and in 2 control gyri—the posterior portion of the inferior temporal gyrus (ITG control) and motor cortex control. Regions of cortical thinning were also compared with signs of retraction injury on early postoperative MRIs. RESULTS Postoperative maps of cortical thickness showed thinning in the inferior temporal gyrus where the retractor was placed in 5 patients. Postoperatively, mean cortical thickness declined from 4.1 ± 0.4 mm to 2.9 ± 0.9 mm in ITG test (P = .03) and was unchanged in the control regions. Anatomically, the region of neocortical thinning correlated with postoperative edema on MRIs obtained within 48 hours of surgery. CONCLUSION Postoperative MRIs can be successfully interrogated for information on cortical thickness. Brain retraction is associated with chronic local thinning of the neocortex. This automated technique may be sensitive enough to detect regions at risk for functional impairment during craniotomy that cannot be easily detected on postoperative structural imaging. BACKGROUND: Brain retraction causes clinically significant postoperative neurological deficits in 3% to 9% of intracranial cases. OBJECTIVE: This study used postoperative magnetic resonance images (MRIs) to determine whether brain retraction caused local anatomic changes to the cerebral neocortex. METHODS: Pre- and postoperative maps of whole-brain cortical thickness were generated from 3-dimensional MRIs of 6 patients who underwent selective amygdalohippocampectomy. Mean cortical thickness was determined in the inferior temporal gyrus (ITG test), where a retractor was placed during surgery, and in 2 control gyri—the posterior portion of the inferior temporal gyrus (ITG control) and motor cortex control. RESULTS: Postoperative maps of cortical thickness showed thinning where the retractor was placed in 5 patients. Postoperatively, mean cortical thickness declined from 4.1 ± 0.4 mm to 2.9 ± 0.9 mm in ITG test (P = .03) and was unchanged in the control regions. Anatomically, the region of neocortical thinning correlated with postoperative edema on MRIs. CONCLUSION: Postoperative MRIs can be successfully interrogated for information on cortical thickness. Brain retraction is associated with chronic local thinning of the neocortex." @default.
• W2046205923 created "2016-06-24" @default.
• W2046205923 creator A5005631326 @default.
• W2046205923 creator A5033435512 @default.
• W2046205923 creator A5040484699 @default.
• W2046205923 creator A5040939351 @default.
• W2046205923 creator A5058133357 @default.
• W2046205923 creator A5064308365 @default.
• W2046205923 creator A5070228075 @default.
• W2046205923 creator A5089950379 @default.
• W2046205923 date "2010-09-01" @default.
• W2046205923 modified "2023-10-12" @default.
• W2046205923 title "Brain Retraction and Thickness of Cerebral Neocortex" @default.
• W2046205923 cites W1510788008 @default.
• W2046205923 cites W2011764527 @default.
• W2046205923 cites W2033200260 @default.
• W2046205923 cites W2053766526 @default.
• W2046205923 cites W2067266908 @default.
• W2046205923 cites W2075123043 @default.
• W2046205923 cites W2076018207 @default.
• W2046205923 cites W2087919730 @default.
• W2046205923 cites W2097942023 @default.
• W2046205923 cites W2099295649 @default.
• W2046205923 cites W2099774304 @default.
• W2046205923 cites W2110208125 @default.
• W2046205923 cites W2151721316 @default.
• W2046205923 cites W2164760908 @default.
• W2046205923 doi "https://doi.org/10.1227/01.neu.0000374699.12150.0" @default.
• W2046205923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20679923" @default.
• W2046205923 hasPublicationYear "2010" @default.
• W2046205923 type Work @default.
• W2046205923 sameAs 2046205923 @default.
• W2046205923 citedByCount "6" @default.
• W2046205923 countsByYear W20462059232012 @default.
• W2046205923 countsByYear W20462059232017 @default.
• W2046205923 countsByYear W20462059232021 @default.
• W2046205923 countsByYear W20462059232022 @default.
• W2046205923 countsByYear W20462059232023 @default.
• W2046205923 crossrefType "journal-article" @default.
• W2046205923 hasAuthorship W2046205923A5005631326 @default.
• W2046205923 hasAuthorship W2046205923A5033435512 @default.
• W2046205923 hasAuthorship W2046205923A5040484699 @default.
• W2046205923 hasAuthorship W2046205923A5040939351 @default.
• W2046205923 hasAuthorship W2046205923A5058133357 @default.
• W2046205923 hasAuthorship W2046205923A5064308365 @default.
• W2046205923 hasAuthorship W2046205923A5070228075 @default.
• W2046205923 hasAuthorship W2046205923A5089950379 @default.
• W2046205923 hasBestOaLocation W20462059231 @default.
• W2046205923 hasConcept C118552586 @default.
• W2046205923 hasConcept C126322002 @default.
• W2046205923 hasConcept C126838900 @default.
• W2046205923 hasConcept C143409427 @default.
• W2046205923 hasConcept C15744967 @default.
• W2046205923 hasConcept C169760540 @default.
• W2046205923 hasConcept C2775956885 @default.
• W2046205923 hasConcept C2777222312 @default.
• W2046205923 hasConcept C2777348757 @default.
• W2046205923 hasConcept C2778186239 @default.
• W2046205923 hasConcept C2779369059 @default.
• W2046205923 hasConcept C2781041448 @default.
• W2046205923 hasConcept C2781099131 @default.
• W2046205923 hasConcept C71924100 @default.
• W2046205923 hasConceptScore W2046205923C118552586 @default.
• W2046205923 hasConceptScore W2046205923C126322002 @default.
• W2046205923 hasConceptScore W2046205923C126838900 @default.
• W2046205923 hasConceptScore W2046205923C143409427 @default.
• W2046205923 hasConceptScore W2046205923C15744967 @default.
• W2046205923 hasConceptScore W2046205923C169760540 @default.
• W2046205923 hasConceptScore W2046205923C2775956885 @default.
• W2046205923 hasConceptScore W2046205923C2777222312 @default.
• W2046205923 hasConceptScore W2046205923C2777348757 @default.
• W2046205923 hasConceptScore W2046205923C2778186239 @default.
• W2046205923 hasConceptScore W2046205923C2779369059 @default.
• W2046205923 hasConceptScore W2046205923C2781041448 @default.
• W2046205923 hasConceptScore W2046205923C2781099131 @default.
• W2046205923 hasConceptScore W2046205923C71924100 @default.
• W2046205923 hasIssue "3" @default.
• W2046205923 hasLocation W20462059231 @default.
• W2046205923 hasLocation W20462059232 @default.
• W2046205923 hasOpenAccess W2046205923 @default.
• W2046205923 hasPrimaryLocation W20462059231 @default.
• W2046205923 hasRelatedWork W1986659399 @default.
• W2046205923 hasRelatedWork W2057524090 @default.
• W2046205923 hasRelatedWork W2062055081 @default.
• W2046205923 hasRelatedWork W2087599741 @default.
• W2046205923 hasRelatedWork W2135835495 @default.
• W2046205923 hasRelatedWork W2273563535 @default.
• W2046205923 hasRelatedWork W2361835542 @default.
• W2046205923 hasRelatedWork W2367866158 @default.
• W2046205923 hasRelatedWork W2381359307 @default.
• W2046205923 hasRelatedWork W2605040249 @default.
• W2046205923 hasVolume "67" @default.
• W2046205923 isParatext "false" @default.
• W2046205923 isRetracted "false" @default.
• W2046205923 magId "2046205923" @default.
• W2046205923 workType "article" @default.