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• W2046207601 abstract "Although a large number of novel broadly neutralizing antibodies has been recently described, the induction of such antibodies via vaccination has proven difficult. By contrast, nonneutralizing antibodies arise early during infection and have been repeatedly associated with both protection from infection and disease progression.We are beginning to gain new insights into the broader landscape of antiviral mechanisms that nonneutralizing antibodies may harness to fight HIV, providing an unprecedented breadth of approaches by which HIV can be blocked and contained.In this review, we summarize the characteristics of nonneutralizing antibodies, their role in HIV infection, and new paradigm-shifting functions that may be exploited by next-generation vaccine approaches aimed at blocking HIV infection." @default.
• W2046207601 created "2016-06-24" @default.
• W2046207601 creator A5009527416 @default.
• W2046207601 creator A5029641235 @default.
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• W2046207601 date "2013-09-01" @default.
• W2046207601 modified "2023-10-08" @default.
• W2046207601 title "New paradigms for functional HIV-specific nonneutralizing antibodies" @default.
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• W2046207601 doi "https://doi.org/10.1097/coh.0b013e328363d486" @default.
• W2046207601 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4097845" @default.
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