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- W2046207876 abstract "B-16 melanoma cells in culture were prelabeled with (3H)-arachidonate, and exposed to UV radiation. Immediately after irradiation the cells released labeled materials. This UV-stimulated release was inhibited by mepacrine (20 μM) and calmodulin inhibitor W7 (0.5 μM). To determine the influence of extracellular Ca2+ on the UV-stimulated release, experiments were made with media containing various concentrations of Ca2+. The release decreased significantly at lower Ca2+ concentrations. These results suggest that Ca2+-calmodulin-dependent phospholipase A2 was involved in UV-stimulated release of radiolabeled materials, possibly arachidonic acid and its metabolites, from the cells." @default.
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- W2046207876 date "1989-03-01" @default.
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- W2046207876 title "Effect of UV-B irradiation on release of arachidonic acid from B-16 melanoma cells" @default.
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- W2046207876 doi "https://doi.org/10.1016/0952-3278(89)90117-8" @default.
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