Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046211002> ?p ?o ?g. }
- W2046211002 endingPage "459" @default.
- W2046211002 startingPage "452" @default.
- W2046211002 abstract "To investigate the thrombotic tendency in patients with systemic lupus erythematosus (SLE) by evaluating congenital or acquired abnormalities associated with an increased risk of venous and/or arterial thrombosis.A total of 57 patients with SLE were included in the study. Twenty-one patients (37%) had a history of arterial and/or venous thrombosis and 36 patients (63%) did not have such a history. Sera from 50 healthy controls were examined. Protein C, protein S, antithrombin, D-dimer, fibrinogen, homocysteine, anticardiolipin antibodies (aCL), lupus anticoagulant (LAC), prothrombin G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T gene mutation were evaluated.Protein C, antithrombin, fibrinogen, D-dimer, and homocysteine levels were significantly higher in patients with SLE than in controls. A prothrombin mutation was observed in 2 (4%) of 50 controls and in 6 (11%) of 57 patients. A significantly higher prevalence (P = 0.036) of MTHFR homozygous mutation was observed in patients with SLE (14 [25%] of 57) in comparison with controls (4 [8%] of 50). IgG-aCL and IgM-aCL levels were significantly higher in patients with SLE than in controls (P < 0.0001). The presence of medium-high (> or = 20 IgG phospholipid units/ml) IgG-aCL antibody titers was significantly higher (P = 0.005) in patients with thrombosis (11 [52%] of 21) than in patients without (5 [14%] of 36) thrombosis. LAC was present in 22 (38.5%) of 57 patients and in none of 50 controls.In this study, we confirm the association between thrombosis and IgG-aCL at medium-high titers and suggest that the coexistence of other risk factors can affect the expression of thrombosis in patients with SLE." @default.
- W2046211002 created "2016-06-24" @default.
- W2046211002 creator A5003621702 @default.
- W2046211002 creator A5003629514 @default.
- W2046211002 creator A5006731401 @default.
- W2046211002 creator A5034479226 @default.
- W2046211002 creator A5035448439 @default.
- W2046211002 creator A5046483009 @default.
- W2046211002 creator A5050542608 @default.
- W2046211002 creator A5051734690 @default.
- W2046211002 creator A5053981273 @default.
- W2046211002 creator A5060732049 @default.
- W2046211002 date "2005-01-01" @default.
- W2046211002 modified "2023-10-14" @default.
- W2046211002 title "Thrombosis in systemic lupus erythematosus: Congenital and acquired risk factors" @default.
- W2046211002 cites W1594237533 @default.
- W2046211002 cites W1596313173 @default.
- W2046211002 cites W1969680510 @default.
- W2046211002 cites W1971977362 @default.
- W2046211002 cites W1973042812 @default.
- W2046211002 cites W1979473764 @default.
- W2046211002 cites W1988309191 @default.
- W2046211002 cites W1989924681 @default.
- W2046211002 cites W1991721757 @default.
- W2046211002 cites W1995781460 @default.
- W2046211002 cites W1996240946 @default.
- W2046211002 cites W2000931975 @default.
- W2046211002 cites W2002788659 @default.
- W2046211002 cites W2025301637 @default.
- W2046211002 cites W2047656798 @default.
- W2046211002 cites W2059943793 @default.
- W2046211002 cites W2070527591 @default.
- W2046211002 cites W2081017805 @default.
- W2046211002 cites W2094025155 @default.
- W2046211002 cites W2109451688 @default.
- W2046211002 cites W2112210780 @default.
- W2046211002 cites W2132823760 @default.
- W2046211002 cites W2146203649 @default.
- W2046211002 cites W2153871972 @default.
- W2046211002 cites W2315578003 @default.
- W2046211002 cites W2318577668 @default.
- W2046211002 cites W2323783182 @default.
- W2046211002 cites W2332313529 @default.
- W2046211002 cites W2408820274 @default.
- W2046211002 cites W2409818507 @default.
- W2046211002 cites W2418894291 @default.
- W2046211002 cites W2462341569 @default.
- W2046211002 cites W2468627657 @default.
- W2046211002 cites W4213347641 @default.
- W2046211002 cites W4256431887 @default.
- W2046211002 cites W4296981399 @default.
- W2046211002 doi "https://doi.org/10.1002/art.21172" @default.
- W2046211002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15934123" @default.
- W2046211002 hasPublicationYear "2005" @default.
- W2046211002 type Work @default.
- W2046211002 sameAs 2046211002 @default.
- W2046211002 citedByCount "63" @default.
- W2046211002 countsByYear W20462110022012 @default.
- W2046211002 countsByYear W20462110022013 @default.
- W2046211002 countsByYear W20462110022014 @default.
- W2046211002 countsByYear W20462110022015 @default.
- W2046211002 countsByYear W20462110022016 @default.
- W2046211002 countsByYear W20462110022017 @default.
- W2046211002 countsByYear W20462110022018 @default.
- W2046211002 countsByYear W20462110022019 @default.
- W2046211002 countsByYear W20462110022020 @default.
- W2046211002 countsByYear W20462110022021 @default.
- W2046211002 countsByYear W20462110022022 @default.
- W2046211002 countsByYear W20462110022023 @default.
- W2046211002 crossrefType "journal-article" @default.
- W2046211002 hasAuthorship W2046211002A5003621702 @default.
- W2046211002 hasAuthorship W2046211002A5003629514 @default.
- W2046211002 hasAuthorship W2046211002A5006731401 @default.
- W2046211002 hasAuthorship W2046211002A5034479226 @default.
- W2046211002 hasAuthorship W2046211002A5035448439 @default.
- W2046211002 hasAuthorship W2046211002A5046483009 @default.
- W2046211002 hasAuthorship W2046211002A5050542608 @default.
- W2046211002 hasAuthorship W2046211002A5051734690 @default.
- W2046211002 hasAuthorship W2046211002A5053981273 @default.
- W2046211002 hasAuthorship W2046211002A5060732049 @default.
- W2046211002 hasBestOaLocation W20462110021 @default.
- W2046211002 hasConcept C104317684 @default.
- W2046211002 hasConcept C126322002 @default.
- W2046211002 hasConcept C135763542 @default.
- W2046211002 hasConcept C185592680 @default.
- W2046211002 hasConcept C203014093 @default.
- W2046211002 hasConcept C2776135265 @default.
- W2046211002 hasConcept C2776523773 @default.
- W2046211002 hasConcept C2777090595 @default.
- W2046211002 hasConcept C2777557582 @default.
- W2046211002 hasConcept C2779026020 @default.
- W2046211002 hasConcept C2779036427 @default.
- W2046211002 hasConcept C2780011451 @default.
- W2046211002 hasConcept C2780022809 @default.
- W2046211002 hasConcept C2780868729 @default.
- W2046211002 hasConcept C43563269 @default.
- W2046211002 hasConcept C55493867 @default.
- W2046211002 hasConcept C71924100 @default.