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- W2046228731 abstract "The arrival of second-generation sequencing has revolutionized the study of bacteria within a short period. The sequence information generated from these platforms has helped in our understanding of bacterial development, adaptation and diversity and how bacteria cause disease. Furthermore, these technologies have quickly been adapted for high-throughput studies that were previously performed using DNA cloning or microarray-based applications. This has facilitated a more comprehensive study of bacterial transcriptomes through RNA sequencing (RNA-Seq) and the systematic determination of gene function by ‘transposon monitoring’. In this review, we provide an outline of these powerful tools and the in silico analyses used in their application, and also highlight the biological questions being addressed in these approaches. The arrival of second-generation sequencing has revolutionized the study of bacteria within a short period. The sequence information generated from these platforms has helped in our understanding of bacterial development, adaptation and diversity and how bacteria cause disease. Furthermore, these technologies have quickly been adapted for high-throughput studies that were previously performed using DNA cloning or microarray-based applications. This has facilitated a more comprehensive study of bacterial transcriptomes through RNA sequencing (RNA-Seq) and the systematic determination of gene function by ‘transposon monitoring’. In this review, we provide an outline of these powerful tools and the in silico analyses used in their application, and also highlight the biological questions being addressed in these approaches." @default.
- W2046228731 created "2016-06-24" @default.
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- W2046228731 date "2011-11-01" @default.
- W2046228731 modified "2023-09-27" @default.
- W2046228731 title "Advances in bacterial transcriptome and transposon insertion-site profiling using second-generation sequencing" @default.
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- W2046228731 cites W1976586739 @default.
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- W2046228731 cites W1981342084 @default.
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- W2046228731 cites W1987139333 @default.
- W2046228731 cites W1987486474 @default.
- W2046228731 cites W1987901589 @default.
- W2046228731 cites W1992770777 @default.
- W2046228731 cites W1994624068 @default.
- W2046228731 cites W1996370379 @default.
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- W2046228731 cites W2022603493 @default.
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- W2046228731 cites W2030924818 @default.
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- W2046228731 doi "https://doi.org/10.1016/j.tibtech.2011.06.004" @default.
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