FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046256807> ?p ?o ?g. }

• W2046256807 endingPage "1132" @default.
• W2046256807 startingPage "1127" @default.
• W2046256807 abstract "Chronic hyperglycemia underlies microvascular complications in patients with type 1 diabetes. The mechanisms leading to these vascular complications are not fully understood. Recently, we observed that acute hyperglycemia results in endothelial glycocalyx damage. To establish whether glycocalyx is associated with microvascular damage, we performed glycocalyx perturbation volume measurements in type 1 diabetic patients with microalbuminuria (DM1-MA group; n = 7), without microalbuminuria (DM1-NA group; n = 7), and in age-matched control subjects (CON; n = 7). Systemic glycocalyx volume was determined comparing intravascular distribution volume of a glycocalyx-permeable tracer (dextran 40) to that of a glycocalyx-impermeable tracer (labeled erythrocytes). Sublingual capillaries were visualized using orthogonal polarization spectral microscopy to estimate microvascular glycocalyx. Patients and control subjects were matched according to age and BMI. Glycocalyx volume decreased in a stepwise fashion from CON, DM1-NA, and finally DM1-MA subjects (1.5 ± 0.1, 0.8 ± 0.4, and 0.2 ± 0.1 l, respectively, P &lt; 0.05). Microvascular glycocalyx in sublingual capillaries was also decreased in type 1 diabetes versus the control group (0.5 ± 0.1 vs. 0.9 ± 0.1 μm, P &lt; 0.05). Plasma hyaluronan, a principal glycocalyx constituent, and hyaluronidase were increased in type 1 diabetes. In conclusion, type 1 diabetic patients are characterized by endothelial glycocalyx damage, the severity of which is increased in presence of microalbuminuria." @default.
• W2046256807 created "2016-06-24" @default.
• W2046256807 creator A5002278102 @default.
• W2046256807 creator A5011260731 @default.
• W2046256807 creator A5015416535 @default.
• W2046256807 creator A5020636730 @default.
• W2046256807 creator A5040981713 @default.
• W2046256807 creator A5044206273 @default.
• W2046256807 creator A5053733278 @default.
• W2046256807 creator A5057342507 @default.
• W2046256807 creator A5068474395 @default.
• W2046256807 creator A5077848934 @default.
• W2046256807 creator A5078587396 @default.
• W2046256807 creator A5081430387 @default.
• W2046256807 creator A5081557648 @default.
• W2046256807 date "2006-04-01" @default.
• W2046256807 modified "2023-10-16" @default.
• W2046256807 title "Endothelial Glycocalyx Damage Coincides With Microalbuminuria in Type 1 Diabetes" @default.
• W2046256807 cites W1599476364 @default.
• W2046256807 cites W1630781445 @default.
• W2046256807 cites W167023063 @default.
• W2046256807 cites W1990917414 @default.
• W2046256807 cites W2004301058 @default.
• W2046256807 cites W2006599075 @default.
• W2046256807 cites W2013093313 @default.
• W2046256807 cites W2015150804 @default.
• W2046256807 cites W2017295052 @default.
• W2046256807 cites W2025011099 @default.
• W2046256807 cites W2044437167 @default.
• W2046256807 cites W2049018734 @default.
• W2046256807 cites W2051875850 @default.
• W2046256807 cites W2063871978 @default.
• W2046256807 cites W2065895195 @default.
• W2046256807 cites W2095154691 @default.
• W2046256807 cites W2133930237 @default.
• W2046256807 cites W2134932415 @default.
• W2046256807 cites W2143269563 @default.
• W2046256807 cites W2143842817 @default.
• W2046256807 cites W2152543475 @default.
• W2046256807 cites W2156156866 @default.
• W2046256807 cites W2157028830 @default.
• W2046256807 cites W2159988004 @default.
• W2046256807 cites W2161938631 @default.
• W2046256807 cites W2162551249 @default.
• W2046256807 cites W2166283593 @default.
• W2046256807 cites W2180631886 @default.
• W2046256807 cites W2282560595 @default.
• W2046256807 cites W2335631045 @default.
• W2046256807 cites W2402354042 @default.
• W2046256807 cites W2769264260 @default.
• W2046256807 cites W4232132230 @default.
• W2046256807 cites W4253337782 @default.
• W2046256807 doi "https://doi.org/10.2337/diabetes.55.04.06.db05-1619" @default.
• W2046256807 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16567538" @default.
• W2046256807 hasPublicationYear "2006" @default.
• W2046256807 type Work @default.
• W2046256807 sameAs 2046256807 @default.
• W2046256807 citedByCount "372" @default.
• W2046256807 countsByYear W20462568072012 @default.
• W2046256807 countsByYear W20462568072013 @default.
• W2046256807 countsByYear W20462568072014 @default.
• W2046256807 countsByYear W20462568072015 @default.
• W2046256807 countsByYear W20462568072016 @default.
• W2046256807 countsByYear W20462568072017 @default.
• W2046256807 countsByYear W20462568072018 @default.
• W2046256807 countsByYear W20462568072019 @default.
• W2046256807 countsByYear W20462568072020 @default.
• W2046256807 countsByYear W20462568072021 @default.
• W2046256807 countsByYear W20462568072022 @default.
• W2046256807 countsByYear W20462568072023 @default.
• W2046256807 crossrefType "journal-article" @default.
• W2046256807 hasAuthorship W2046256807A5002278102 @default.
• W2046256807 hasAuthorship W2046256807A5011260731 @default.
• W2046256807 hasAuthorship W2046256807A5015416535 @default.
• W2046256807 hasAuthorship W2046256807A5020636730 @default.
• W2046256807 hasAuthorship W2046256807A5040981713 @default.
• W2046256807 hasAuthorship W2046256807A5044206273 @default.
• W2046256807 hasAuthorship W2046256807A5053733278 @default.
• W2046256807 hasAuthorship W2046256807A5057342507 @default.
• W2046256807 hasAuthorship W2046256807A5068474395 @default.
• W2046256807 hasAuthorship W2046256807A5077848934 @default.
• W2046256807 hasAuthorship W2046256807A5078587396 @default.
• W2046256807 hasAuthorship W2046256807A5081430387 @default.
• W2046256807 hasAuthorship W2046256807A5081557648 @default.
• W2046256807 hasBestOaLocation W20462568071 @default.
• W2046256807 hasConcept C126322002 @default.
• W2046256807 hasConcept C134018914 @default.
• W2046256807 hasConcept C203014093 @default.
• W2046256807 hasConcept C2777180221 @default.
• W2046256807 hasConcept C2780098789 @default.
• W2046256807 hasConcept C2781203188 @default.
• W2046256807 hasConcept C555293320 @default.
• W2046256807 hasConcept C71924100 @default.
• W2046256807 hasConceptScore W2046256807C126322002 @default.
• W2046256807 hasConceptScore W2046256807C134018914 @default.
• W2046256807 hasConceptScore W2046256807C203014093 @default.
• W2046256807 hasConceptScore W2046256807C2777180221 @default.
• W2046256807 hasConceptScore W2046256807C2780098789 @default.

• next