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• W2046271704 startingPage "S1237" @default.
• W2046271704 abstract "In the recent years of research, the interest on herbal medicine is continuously increasing. Piperine is an alkaloid extracted from ripen fruits of Piper nigram and was proved in literature for its hepato protective and anti ulcer properties majorly through anti oxidant capability. In the present investigation gastro retentive, both floating and mucoadhessive microspheres are evaluated for the hepato protection in paracetamol induced model and gastric protection in rats and a comparison was done with conventional microspheres and pure form of piperine. The results clearly showed the significant decrease in the serum levels of the marker enzymes in hepato protective study supported by histopathology along with reduced ulcer index in anti ulcer activity. This clearly indicates that there is an increase in both activities of floating microspheres, mucoadhessive microspheres when compared with the PP and conventional microspheres." @default.
• W2046271704 created "2016-06-24" @default.
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• W2046271704 date "2012-01-01" @default.
• W2046271704 modified "2023-09-27" @default.
• W2046271704 title "In vitro and invivo evaluation of hepato protection and anti ulcer activities of piperine gastro retentive micropspheres" @default.
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• W2046271704 doi "https://doi.org/10.1016/s2221-1691(12)60392-x" @default.
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