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- W2046286119 abstract "Polarization-resolved, second harmonic generation (P-SHG) microscopy is utilized for medical diagnosis of pathological skin dermis. We acquired the pitch angle of collagen fiber from the P-SHG microscopy. In analyzing the large area, pixel by pixel of normal and pathological skin dermis, we found that excessive proliferation of collagen fiber (EPC) and dissolution of elastic fiber (DEF) characterize pathological skin dermis. In addition, the pitch angle of normal skin was found to be 52.01±0.96, while pathological skin EPC and DEF were found to be 48.68±1.49 and 48.09±1.83. It is found that pitch angle of pathological dermis trend to smaller angle, below 50 degree, and wider distribution, 2 times over the normal." @default.
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- W2046286119 date "2009-02-01" @default.
- W2046286119 modified "2023-09-29" @default.
- W2046286119 title "Imaging Collagen for Normal and Pathological Skin Dermis through Polarization-Resolved Second Harmonic Generation" @default.
- W2046286119 doi "https://doi.org/10.1016/j.bpj.2008.12.1463" @default.
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