Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046323455> ?p ?o ?g. }
- W2046323455 endingPage "133" @default.
- W2046323455 startingPage "119" @default.
- W2046323455 abstract "Adrenal corticosteroids (cortisol in humans or corticosterone in rodents) exert numerous effects in the central nervous system that regulate the stress response, mood, learning and memory, and various neuroendocrine functions. Corticosterone actions in the brain are mediated by two corticosteroid receptors, glucocorticoid receptor (GR) and mineralocorticoid receptor (MR), and they show a high degree of colocalization in the hippocampal region. These receptors predominantly reside in the cytoplasm without ligand and are translocated into the nucleus upon ligand binding to act as transcriptional factors. Thus, their subcellualr localizations are an important component of their biological activity. Given the differential action of MR and GR in the central nervous system, it is important to elucidate how the trafficking of these receptors between the cytoplasm and the nucleus and their interactions are regulated by ligand or other molecules to exert transcriptional activity. In this review, the authors focus on the nucleocytoplasmic and subnuclear trafficking of GR and MR in neural cells and nonneural cells and discuss various factors affecting the dynamics of these receptors." @default.
- W2046323455 created "2016-06-24" @default.
- W2046323455 creator A5017800234 @default.
- W2046323455 creator A5032604571 @default.
- W2046323455 date "2006-04-01" @default.
- W2046323455 modified "2023-10-18" @default.
- W2046323455 title "Brain Corticosteroid Receptor Dynamics and Trafficking: Implications from Live Cell Imaging" @default.
- W2046323455 cites W1213045642 @default.
- W2046323455 cites W1507538191 @default.
- W2046323455 cites W1527191068 @default.
- W2046323455 cites W1530952467 @default.
- W2046323455 cites W1534019559 @default.
- W2046323455 cites W1544900705 @default.
- W2046323455 cites W1563232002 @default.
- W2046323455 cites W1565506774 @default.
- W2046323455 cites W1577554347 @default.
- W2046323455 cites W1596797500 @default.
- W2046323455 cites W1613446635 @default.
- W2046323455 cites W1631244035 @default.
- W2046323455 cites W1635552303 @default.
- W2046323455 cites W1675708121 @default.
- W2046323455 cites W1804267428 @default.
- W2046323455 cites W1846296194 @default.
- W2046323455 cites W1856360008 @default.
- W2046323455 cites W1941419571 @default.
- W2046323455 cites W1963679764 @default.
- W2046323455 cites W1964315599 @default.
- W2046323455 cites W1967179182 @default.
- W2046323455 cites W1967658150 @default.
- W2046323455 cites W1969215672 @default.
- W2046323455 cites W1973775511 @default.
- W2046323455 cites W1974950683 @default.
- W2046323455 cites W1975574477 @default.
- W2046323455 cites W1979966145 @default.
- W2046323455 cites W1987040411 @default.
- W2046323455 cites W1988863726 @default.
- W2046323455 cites W1989867542 @default.
- W2046323455 cites W1994320348 @default.
- W2046323455 cites W2003196551 @default.
- W2046323455 cites W2003928686 @default.
- W2046323455 cites W2007323865 @default.
- W2046323455 cites W2009975411 @default.
- W2046323455 cites W2013640714 @default.
- W2046323455 cites W2014378552 @default.
- W2046323455 cites W2018095466 @default.
- W2046323455 cites W2019312435 @default.
- W2046323455 cites W2020836116 @default.
- W2046323455 cites W2024566047 @default.
- W2046323455 cites W2026277788 @default.
- W2046323455 cites W2027576518 @default.
- W2046323455 cites W2031667205 @default.
- W2046323455 cites W2031752348 @default.
- W2046323455 cites W2032579724 @default.
- W2046323455 cites W2040476467 @default.
- W2046323455 cites W2040762618 @default.
- W2046323455 cites W2044768708 @default.
- W2046323455 cites W2045431263 @default.
- W2046323455 cites W2046252690 @default.
- W2046323455 cites W2048813075 @default.
- W2046323455 cites W2049793619 @default.
- W2046323455 cites W2050018101 @default.
- W2046323455 cites W2050306462 @default.
- W2046323455 cites W2051715358 @default.
- W2046323455 cites W2052059014 @default.
- W2046323455 cites W2055161357 @default.
- W2046323455 cites W2055561880 @default.
- W2046323455 cites W2062834772 @default.
- W2046323455 cites W2063110155 @default.
- W2046323455 cites W2067481123 @default.
- W2046323455 cites W2067574381 @default.
- W2046323455 cites W2070059730 @default.
- W2046323455 cites W2070126991 @default.
- W2046323455 cites W2073615418 @default.
- W2046323455 cites W2074802748 @default.
- W2046323455 cites W2077604073 @default.
- W2046323455 cites W2078950703 @default.
- W2046323455 cites W2079462030 @default.
- W2046323455 cites W2079780982 @default.
- W2046323455 cites W2080118525 @default.
- W2046323455 cites W2083007693 @default.
- W2046323455 cites W2083464743 @default.
- W2046323455 cites W2086378163 @default.
- W2046323455 cites W2088766302 @default.
- W2046323455 cites W2093164343 @default.
- W2046323455 cites W2093287522 @default.
- W2046323455 cites W2093685381 @default.
- W2046323455 cites W2095395905 @default.
- W2046323455 cites W2095465583 @default.
- W2046323455 cites W2095503890 @default.
- W2046323455 cites W2096594220 @default.
- W2046323455 cites W2096774529 @default.
- W2046323455 cites W2104360623 @default.
- W2046323455 cites W2112022185 @default.
- W2046323455 cites W2112946281 @default.
- W2046323455 cites W2117763054 @default.
- W2046323455 cites W2119096223 @default.
- W2046323455 cites W2120482660 @default.
- W2046323455 cites W2125099281 @default.