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- W2046336316 abstract "Ionic lanthanum preferentially outlined the lateral and basal membranes of the mitochondria-rich cell in toad bladder epithelium. The electrophysiological responses of bladders exposed to lanthanum were determined. After 15 min exposure, vasopressin and cAMP elicited an increase in transepithelial Na+ transport, but the hydro-osmotic response normally evoked by vasopressin was 85% inhibited. These findings suggest that lanthanum is replacing calcium in the membranes. As the time of serosal exposure to lanthanum increased, a steady drop in resistance occurred, which was correlated with a toxic effect on the epithelium. After 1 hr exposure, the cells appeared swollen, had large vacuoles and their intercellular spaces were dilated. After 2 hr, extensive alterations were observed and some cells were detaching from the underlying layers, but tight junctions appeared intact. The preferential lanthanum “staining” demonstrates that the lateral and basal membranes of the mitochondria rich cell differ from those of the other cells comprising the epithelium." @default.
- W2046336316 created "2016-06-24" @default.
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- W2046336316 date "1977-05-01" @default.
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- W2046336316 title "Lanthanum “Staining” of the lateral and basal membranes of the mitochondria-rich cell in toad bladder epithelium" @default.
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- W2046336316 doi "https://doi.org/10.1016/s0022-5320(77)80073-7" @default.
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