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• W2046336742 abstract "The farnesoid X receptor (FXR) may play a crucial role in a number of metabolic diseases and, as such, could potentially serve as a target for the development of therapeutics as a treatment for those diseases. Previous work has described GW4064 as an FXR agonist with an interesting activity profile. This manuscript will describe the synthesis of novel analogs of GW4064 and the activity profile of those analogs." @default.
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• W2046336742 date "2015-01-01" @default.
• W2046336742 modified "2023-09-30" @default.
• W2046336742 title "Novel heterocyclic scaffolds of GW4064 as farnesoid X receptor agonists" @default.
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• W2046336742 doi "https://doi.org/10.1016/j.bmcl.2014.11.050" @default.
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