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- W2046340314 abstract "We measured the contents of anti-tumor polysaccharides in certain mushrooms using the two kinds of antibodies that specifically recognize lentinan and GGF, which were isolated from Lentinus edodes and Grifola frondosa, respectively, as β-glucans of these polysaccharides. To determine which mushrooms showed immunomodulating activity, the TNF-α and NO productions of mouse peritoneal macrophages and the subset analysis of splenic lymphocytes stimulated with a polysaccharide from each mushroom were examined. It was ascertained that polysaccharides from mushrooms that enhanced NO production also elicited TNF-α production and that mushrooms containing the positive polysaccharides to anti-lentinan and anti-GGF antibodies at least augmented the production of TNF-α and NO. Furthermore, the polysaccharides from Fammulina velutipes and Meripilus giganteu increased lymphocyte T cell subsets. Therefore, we demonstrated that those polysaccharides had high levels of immunomodulating activity." @default.
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- W2046340314 date "2001-01-01" @default.
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- W2046340314 title "Contents of Anti-Tumor Polysaccharides in Certain Mushrooms and Their Immunomodulating Activities." @default.
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- W2046340314 doi "https://doi.org/10.3136/fstr.7.31" @default.
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