FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046345522> ?p ?o ?g. }

• W2046345522 endingPage "288" @default.
• W2046345522 startingPage "285" @default.
• W2046345522 abstract "The multifunctional proteins, basic fibroblast growth factor (bFGF) and ciliary neurotrophic factor (CNTF), share a capacity to promote in vitro and in vivo survival of several, partly overlapping neuron populations. Whether they can affect neurons directly or whether their supportive effects are mediated by non-neuronal cells and their growth factor products has been addressed in this study by establishing single neuron cultures from embryonic chick ciliary ganglia. Cultures with one or two neurons and without any non-neuronal cells were obtained by limiting dilution of ganglionic cell suspensions on 96-well microtiter plates. In the presence of bFGF about 80% of the wells that contained 1 or 2 neurons at the time of seeding, had this (these) neuron(s) maintained after 1 and 5 days. Absence of bFGF resulted in the death of neurons in over 80% of the wells screened. Identical results were obtained with CNTF. These data demonstrate the effectiveness of bFGF and CNTF at the single neuron level, but do not rule out that the factors may act indirectly on neurons, particularly in complex in vitro and in vivo situations." @default.
• W2046345522 created "2016-06-24" @default.
• W2046345522 creator A5046498647 @default.
• W2046345522 creator A5047686228 @default.
• W2046345522 creator A5081887477 @default.
• W2046345522 date "1992-02-01" @default.
• W2046345522 modified "2023-09-27" @default.
• W2046345522 title "Stimulation of neuron survival by basic FGF and CNTF is a direct effect and not mediated by non-neuronal cells: evidence from single cell cultures" @default.
• W2046345522 cites W116915451 @default.
• W2046345522 cites W1503786837 @default.
• W2046345522 cites W1964502521 @default.
• W2046345522 cites W1976652850 @default.
• W2046345522 cites W1985933922 @default.
• W2046345522 cites W1991372941 @default.
• W2046345522 cites W1992129124 @default.
• W2046345522 cites W1994365433 @default.
• W2046345522 cites W2008426347 @default.
• W2046345522 cites W2011469489 @default.
• W2046345522 cites W2019956654 @default.
• W2046345522 cites W2021092333 @default.
• W2046345522 cites W2021418176 @default.
• W2046345522 cites W2023488853 @default.
• W2046345522 cites W2033374103 @default.
• W2046345522 cites W2041442694 @default.
• W2046345522 cites W2046739492 @default.
• W2046345522 cites W2051485994 @default.
• W2046345522 cites W2052969012 @default.
• W2046345522 cites W2055164554 @default.
• W2046345522 cites W2059566787 @default.
• W2046345522 cites W2064739683 @default.
• W2046345522 cites W2105310604 @default.
• W2046345522 cites W2146119530 @default.
• W2046345522 doi "https://doi.org/10.1016/0165-3806(92)90191-x" @default.
• W2046345522 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1572071" @default.
• W2046345522 hasPublicationYear "1992" @default.
• W2046345522 type Work @default.
• W2046345522 sameAs 2046345522 @default.
• W2046345522 citedByCount "64" @default.
• W2046345522 countsByYear W20463455222012 @default.
• W2046345522 countsByYear W20463455222015 @default.
• W2046345522 countsByYear W20463455222016 @default.
• W2046345522 countsByYear W20463455222019 @default.
• W2046345522 countsByYear W20463455222020 @default.
• W2046345522 crossrefType "journal-article" @default.
• W2046345522 hasAuthorship W2046345522A5046498647 @default.
• W2046345522 hasAuthorship W2046345522A5047686228 @default.
• W2046345522 hasAuthorship W2046345522A5081887477 @default.
• W2046345522 hasConcept C104317684 @default.
• W2046345522 hasConcept C145103041 @default.
• W2046345522 hasConcept C160539049 @default.
• W2046345522 hasConcept C169760540 @default.
• W2046345522 hasConcept C170493617 @default.
• W2046345522 hasConcept C207001950 @default.
• W2046345522 hasConcept C24998067 @default.
• W2046345522 hasConcept C2775960820 @default.
• W2046345522 hasConcept C2777587049 @default.
• W2046345522 hasConcept C2778794669 @default.
• W2046345522 hasConcept C54355233 @default.
• W2046345522 hasConcept C55493867 @default.
• W2046345522 hasConcept C68710172 @default.
• W2046345522 hasConcept C74373430 @default.
• W2046345522 hasConcept C86803240 @default.
• W2046345522 hasConcept C92020748 @default.
• W2046345522 hasConcept C95444343 @default.
• W2046345522 hasConceptScore W2046345522C104317684 @default.
• W2046345522 hasConceptScore W2046345522C145103041 @default.
• W2046345522 hasConceptScore W2046345522C160539049 @default.
• W2046345522 hasConceptScore W2046345522C169760540 @default.
• W2046345522 hasConceptScore W2046345522C170493617 @default.
• W2046345522 hasConceptScore W2046345522C207001950 @default.
• W2046345522 hasConceptScore W2046345522C24998067 @default.
• W2046345522 hasConceptScore W2046345522C2775960820 @default.
• W2046345522 hasConceptScore W2046345522C2777587049 @default.
• W2046345522 hasConceptScore W2046345522C2778794669 @default.
• W2046345522 hasConceptScore W2046345522C54355233 @default.
• W2046345522 hasConceptScore W2046345522C55493867 @default.
• W2046345522 hasConceptScore W2046345522C68710172 @default.
• W2046345522 hasConceptScore W2046345522C74373430 @default.
• W2046345522 hasConceptScore W2046345522C86803240 @default.
• W2046345522 hasConceptScore W2046345522C92020748 @default.
• W2046345522 hasConceptScore W2046345522C95444343 @default.
• W2046345522 hasIssue "2" @default.
• W2046345522 hasLocation W20463455221 @default.
• W2046345522 hasLocation W20463455222 @default.
• W2046345522 hasOpenAccess W2046345522 @default.
• W2046345522 hasPrimaryLocation W20463455221 @default.
• W2046345522 hasRelatedWork W1499757659 @default.
• W2046345522 hasRelatedWork W1974084948 @default.
• W2046345522 hasRelatedWork W2003811067 @default.
• W2046345522 hasRelatedWork W2023363182 @default.
• W2046345522 hasRelatedWork W2028820273 @default.
• W2046345522 hasRelatedWork W2073218812 @default.
• W2046345522 hasRelatedWork W2126714637 @default.
• W2046345522 hasRelatedWork W2320073138 @default.
• W2046345522 hasRelatedWork W2351152809 @default.
• W2046345522 hasRelatedWork W2390708766 @default.
• W2046345522 hasVolume "65" @default.
• W2046345522 isParatext "false" @default.

• next