Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046349892> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2046349892 endingPage "338" @default.
- W2046349892 startingPage "332" @default.
- W2046349892 abstract "We recently designed and constructed chimeric proteins for the elimination of specific cell populations. These chimeric proteins are composed of a targeting component fused to an apoptotic protein as the killing moiety. However, chimeric proteins can serve not only to eliminate cell populations, but also as “biological tools” for studying the fate of endogenous proteins. We show here that upon entering their target cell, a variety of chimeric proteins composed of an endogenous protein as their killing moiety reach the subcellular location of their endogenous counterpart. In contrast, bacterial-based killing domains head for the subcellular site of their substrate. Moreover, the chimeric protein acts similarly to the endogenous protein, while causing the cell to die. Therefore, chimeric proteins may serve as a unique tool for investigating cellular proteins and their intracellular localization, without the need to overexpress them." @default.
- W2046349892 created "2016-06-24" @default.
- W2046349892 creator A5006753320 @default.
- W2046349892 creator A5021249524 @default.
- W2046349892 creator A5033423836 @default.
- W2046349892 creator A5034697098 @default.
- W2046349892 creator A5065848662 @default.
- W2046349892 date "2002-01-01" @default.
- W2046349892 modified "2023-09-27" @default.
- W2046349892 title "Utilizing Chimeric Proteins for Exploring the Cellular Fate of Endogenous Proteins" @default.
- W2046349892 cites W1501945442 @default.
- W2046349892 cites W1551872601 @default.
- W2046349892 cites W1677605583 @default.
- W2046349892 cites W181227182 @default.
- W2046349892 cites W1977680104 @default.
- W2046349892 cites W1980462656 @default.
- W2046349892 cites W1994611236 @default.
- W2046349892 cites W2005698990 @default.
- W2046349892 cites W2014335282 @default.
- W2046349892 cites W2025976409 @default.
- W2046349892 cites W2027671103 @default.
- W2046349892 cites W2049326023 @default.
- W2046349892 cites W2051871378 @default.
- W2046349892 cites W2054100508 @default.
- W2046349892 cites W2061757655 @default.
- W2046349892 cites W2061879337 @default.
- W2046349892 cites W2070218019 @default.
- W2046349892 cites W2070862399 @default.
- W2046349892 cites W2076434801 @default.
- W2046349892 cites W2086883099 @default.
- W2046349892 cites W2088383049 @default.
- W2046349892 cites W2092101339 @default.
- W2046349892 cites W2096056358 @default.
- W2046349892 cites W2115172049 @default.
- W2046349892 cites W2132411546 @default.
- W2046349892 cites W2162441925 @default.
- W2046349892 cites W2171365668 @default.
- W2046349892 cites W2177651721 @default.
- W2046349892 cites W2217146256 @default.
- W2046349892 cites W2317926428 @default.
- W2046349892 cites W2332293452 @default.
- W2046349892 cites W4236598197 @default.
- W2046349892 doi "https://doi.org/10.1006/bbrc.2001.6163" @default.
- W2046349892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11779174" @default.
- W2046349892 hasPublicationYear "2002" @default.
- W2046349892 type Work @default.
- W2046349892 sameAs 2046349892 @default.
- W2046349892 citedByCount "3" @default.
- W2046349892 crossrefType "journal-article" @default.
- W2046349892 hasAuthorship W2046349892A5006753320 @default.
- W2046349892 hasAuthorship W2046349892A5021249524 @default.
- W2046349892 hasAuthorship W2046349892A5033423836 @default.
- W2046349892 hasAuthorship W2046349892A5034697098 @default.
- W2046349892 hasAuthorship W2046349892A5065848662 @default.
- W2046349892 hasConcept C104317684 @default.
- W2046349892 hasConcept C123894998 @default.
- W2046349892 hasConcept C1491633281 @default.
- W2046349892 hasConcept C16613235 @default.
- W2046349892 hasConcept C40767141 @default.
- W2046349892 hasConcept C55493867 @default.
- W2046349892 hasConcept C79879829 @default.
- W2046349892 hasConcept C86803240 @default.
- W2046349892 hasConcept C95444343 @default.
- W2046349892 hasConceptScore W2046349892C104317684 @default.
- W2046349892 hasConceptScore W2046349892C123894998 @default.
- W2046349892 hasConceptScore W2046349892C1491633281 @default.
- W2046349892 hasConceptScore W2046349892C16613235 @default.
- W2046349892 hasConceptScore W2046349892C40767141 @default.
- W2046349892 hasConceptScore W2046349892C55493867 @default.
- W2046349892 hasConceptScore W2046349892C79879829 @default.
- W2046349892 hasConceptScore W2046349892C86803240 @default.
- W2046349892 hasConceptScore W2046349892C95444343 @default.
- W2046349892 hasIssue "1" @default.
- W2046349892 hasLocation W20463498921 @default.
- W2046349892 hasLocation W20463498922 @default.
- W2046349892 hasOpenAccess W2046349892 @default.
- W2046349892 hasPrimaryLocation W20463498921 @default.
- W2046349892 hasRelatedWork W1569629748 @default.
- W2046349892 hasRelatedWork W2026264997 @default.
- W2046349892 hasRelatedWork W2042678520 @default.
- W2046349892 hasRelatedWork W2071063451 @default.
- W2046349892 hasRelatedWork W2519299873 @default.
- W2046349892 hasRelatedWork W2913645037 @default.
- W2046349892 hasRelatedWork W2982026026 @default.
- W2046349892 hasRelatedWork W3021061361 @default.
- W2046349892 hasRelatedWork W4280591137 @default.
- W2046349892 hasRelatedWork W4365443771 @default.
- W2046349892 hasVolume "290" @default.
- W2046349892 isParatext "false" @default.
- W2046349892 isRetracted "false" @default.
- W2046349892 magId "2046349892" @default.
- W2046349892 workType "article" @default.