Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046443345> ?p ?o ?g. }
- W2046443345 endingPage "3646" @default.
- W2046443345 startingPage "3638" @default.
- W2046443345 abstract "Our current results, aimed at the detection of protein abundance alterations that could be associated with the process of colon tumorigenesis, are summarized. The matched sets of macroscopically normal colon mucosa and colorectal carcinoma were examined by a one- or two-dimensional electrophoretic approach and proteins were identified using immunoblotting or mass spectrometry. The following results were observed: The levels of liver fatty acid-binding protein, actin-binding protein/smooth muscle protein 22-alpha and cyclooxygenase 2 were downregulated in colorectal carcinoma compared to normal colon mucosa. Conversely, the expression of a novel variant of heat shock protein70 and several members of the S100 protein family of calcium-binding proteins (two isoforms of S100A9, S100A8, S100A11 and S100A6) were upregulated in transformed colon mucosa. Despite the variations of the levels of expression of given protein among analyzed samples, all quantitative changes were found to be statistically significant (Mann-Whitney test assuming p < or = 0.05). We conclude that the proteomic approach is useful for the study of complex biological events underlying the process of colorectal tumorigenesis." @default.
- W2046443345 created "2016-06-24" @default.
- W2046443345 creator A5007237970 @default.
- W2046443345 creator A5009571380 @default.
- W2046443345 creator A5026061981 @default.
- W2046443345 creator A5028049448 @default.
- W2046443345 creator A5035736182 @default.
- W2046443345 creator A5039379035 @default.
- W2046443345 creator A5049199162 @default.
- W2046443345 creator A5050226871 @default.
- W2046443345 creator A5054875063 @default.
- W2046443345 creator A5070106223 @default.
- W2046443345 date "1999-12-01" @default.
- W2046443345 modified "2023-10-03" @default.
- W2046443345 title "Protein abundance alterations in matched sets of macroscopically normal colon mucosa and colorectal carcinoma" @default.
- W2046443345 cites W1820189410 @default.
- W2046443345 cites W1878762030 @default.
- W2046443345 cites W1921905412 @default.
- W2046443345 cites W1964498325 @default.
- W2046443345 cites W1975085160 @default.
- W2046443345 cites W1975495263 @default.
- W2046443345 cites W1981637107 @default.
- W2046443345 cites W1985550503 @default.
- W2046443345 cites W1994613028 @default.
- W2046443345 cites W1996381321 @default.
- W2046443345 cites W1998243306 @default.
- W2046443345 cites W2007655613 @default.
- W2046443345 cites W2012901550 @default.
- W2046443345 cites W2021398185 @default.
- W2046443345 cites W2021415747 @default.
- W2046443345 cites W2021962948 @default.
- W2046443345 cites W2025391005 @default.
- W2046443345 cites W2046345325 @default.
- W2046443345 cites W2049003765 @default.
- W2046443345 cites W2051686420 @default.
- W2046443345 cites W2054784080 @default.
- W2046443345 cites W2055267088 @default.
- W2046443345 cites W2057855646 @default.
- W2046443345 cites W2058169139 @default.
- W2046443345 cites W2071192671 @default.
- W2046443345 cites W2072942230 @default.
- W2046443345 cites W2079054436 @default.
- W2046443345 cites W2100837269 @default.
- W2046443345 cites W2101765347 @default.
- W2046443345 cites W2102071794 @default.
- W2046443345 cites W2102131116 @default.
- W2046443345 cites W2103874799 @default.
- W2046443345 cites W2135878387 @default.
- W2046443345 cites W2144578507 @default.
- W2046443345 cites W2154824578 @default.
- W2046443345 cites W2160292264 @default.
- W2046443345 cites W2474134817 @default.
- W2046443345 cites W4244082907 @default.
- W2046443345 doi "https://doi.org/10.1002/(sici)1522-2683(19991201)20:18<3638::aid-elps3638>3.0.co;2-w" @default.
- W2046443345 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10612291" @default.
- W2046443345 hasPublicationYear "1999" @default.
- W2046443345 type Work @default.
- W2046443345 sameAs 2046443345 @default.
- W2046443345 citedByCount "77" @default.
- W2046443345 countsByYear W20464433452012 @default.
- W2046443345 countsByYear W20464433452013 @default.
- W2046443345 countsByYear W20464433452014 @default.
- W2046443345 countsByYear W20464433452015 @default.
- W2046443345 countsByYear W20464433452016 @default.
- W2046443345 countsByYear W20464433452019 @default.
- W2046443345 countsByYear W20464433452020 @default.
- W2046443345 countsByYear W20464433452021 @default.
- W2046443345 countsByYear W20464433452023 @default.
- W2046443345 crossrefType "journal-article" @default.
- W2046443345 hasAuthorship W2046443345A5007237970 @default.
- W2046443345 hasAuthorship W2046443345A5009571380 @default.
- W2046443345 hasAuthorship W2046443345A5026061981 @default.
- W2046443345 hasAuthorship W2046443345A5028049448 @default.
- W2046443345 hasAuthorship W2046443345A5035736182 @default.
- W2046443345 hasAuthorship W2046443345A5039379035 @default.
- W2046443345 hasAuthorship W2046443345A5049199162 @default.
- W2046443345 hasAuthorship W2046443345A5050226871 @default.
- W2046443345 hasAuthorship W2046443345A5054875063 @default.
- W2046443345 hasAuthorship W2046443345A5070106223 @default.
- W2046443345 hasConcept C104317684 @default.
- W2046443345 hasConcept C121608353 @default.
- W2046443345 hasConcept C126322002 @default.
- W2046443345 hasConcept C142724271 @default.
- W2046443345 hasConcept C153911025 @default.
- W2046443345 hasConcept C203014093 @default.
- W2046443345 hasConcept C2776307749 @default.
- W2046443345 hasConcept C2776914184 @default.
- W2046443345 hasConcept C2777546739 @default.
- W2046443345 hasConcept C2778557267 @default.
- W2046443345 hasConcept C3019368612 @default.
- W2046443345 hasConcept C46111723 @default.
- W2046443345 hasConcept C526805850 @default.
- W2046443345 hasConcept C53345823 @default.
- W2046443345 hasConcept C55493867 @default.
- W2046443345 hasConcept C555283112 @default.
- W2046443345 hasConcept C71924100 @default.
- W2046443345 hasConcept C86803240 @default.
- W2046443345 hasConceptScore W2046443345C104317684 @default.