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- W2046471358 endingPage "350" @default.
- W2046471358 startingPage "338" @default.
- W2046471358 abstract "Subjects exposed to arsenic show significant inter-individual variation in urinary patterns of arsenic metabolites but insignificant day-to-day intra-individual variation. The inter-individual variation in arsenic methylation can be partly responsible for the variation in susceptibility to arsenic toxicity. Wide inter-ethnic variation and family correlation in urinary arsenic profile suggest a genetic effect on arsenic metabolism. In this paper the environmental factors affecting arsenic metabolism are reviewed. Methylation capacity might reduce with increasing dosage of arsenic exposure. Furthermore, women, especially at pregnancy, have better methylation capacity than their men counterparts, probably due to the effect of estrogen. Children might have better methylation capacity than adults and age shows inconsistent relevance in adults. Smoking and alcohol consumption might be associated with a poorer methylation capacity. Nutritional status is important in the methylation capacity and folate may facilitate the methylation and excretion of arsenic. Besides, general health conditions and medications might influence the arsenic methylation capacity; and technical problems can cause biased estimates. The consumption of seafood, seaweed, rice and other food with high arsenic contents and the extent of cooking and arsenic-containing water used in food preparation may also interfere with the presentation of the urinary arsenic profile. Future studies are necessary to clarify the effects of the various arsenic metabolites including the trivalent methylated forms on the development of arsenic-induced human diseases with the consideration of the effects of confounding factors and the interactions with other effect modifiers." @default.
- W2046471358 created "2016-06-24" @default.
- W2046471358 creator A5038889667 @default.
- W2046471358 date "2009-03-15" @default.
- W2046471358 modified "2023-10-01" @default.
- W2046471358 title "A review on environmental factors regulating arsenic methylation in humans" @default.
- W2046471358 cites W117048748 @default.
- W2046471358 cites W1780646802 @default.
- W2046471358 cites W1848079218 @default.
- W2046471358 cites W1870320833 @default.
- W2046471358 cites W1893109445 @default.
- W2046471358 cites W1896003389 @default.
- W2046471358 cites W1896294955 @default.
- W2046471358 cites W1948184580 @default.
- W2046471358 cites W1974396643 @default.
- W2046471358 cites W1974992756 @default.
- W2046471358 cites W1977707491 @default.
- W2046471358 cites W1978540552 @default.
- W2046471358 cites W1980852410 @default.
- W2046471358 cites W1982180050 @default.
- W2046471358 cites W1983688369 @default.
- W2046471358 cites W1986264678 @default.
- W2046471358 cites W1986789470 @default.
- W2046471358 cites W1988852471 @default.
- W2046471358 cites W1990452086 @default.
- W2046471358 cites W1990994253 @default.
- W2046471358 cites W1993433097 @default.
- W2046471358 cites W1995338674 @default.
- W2046471358 cites W1997565776 @default.
- W2046471358 cites W1999899529 @default.
- W2046471358 cites W2001608805 @default.
- W2046471358 cites W2003024378 @default.
- W2046471358 cites W2003525359 @default.
- W2046471358 cites W2005802710 @default.
- W2046471358 cites W2006169808 @default.
- W2046471358 cites W2010081853 @default.
- W2046471358 cites W2011221150 @default.
- W2046471358 cites W2011234751 @default.
- W2046471358 cites W2011388076 @default.
- W2046471358 cites W2014584761 @default.
- W2046471358 cites W2015138846 @default.
- W2046471358 cites W2016902028 @default.
- W2046471358 cites W2018655835 @default.
- W2046471358 cites W2020820075 @default.
- W2046471358 cites W2024588710 @default.
- W2046471358 cites W2025474555 @default.
- W2046471358 cites W2026920894 @default.
- W2046471358 cites W2030107842 @default.
- W2046471358 cites W2030166740 @default.
- W2046471358 cites W2031299813 @default.
- W2046471358 cites W2035756657 @default.
- W2046471358 cites W2036860239 @default.
- W2046471358 cites W2037960524 @default.
- W2046471358 cites W2038511792 @default.
- W2046471358 cites W2042249627 @default.
- W2046471358 cites W2042883972 @default.
- W2046471358 cites W2046155936 @default.
- W2046471358 cites W204678237 @default.
- W2046471358 cites W2047454507 @default.
- W2046471358 cites W2047975812 @default.
- W2046471358 cites W2048859385 @default.
- W2046471358 cites W2050911272 @default.
- W2046471358 cites W2051384809 @default.
- W2046471358 cites W2053578001 @default.
- W2046471358 cites W2057119453 @default.
- W2046471358 cites W2063492468 @default.
- W2046471358 cites W2071500283 @default.
- W2046471358 cites W2079017256 @default.
- W2046471358 cites W2080723247 @default.
- W2046471358 cites W2081371563 @default.
- W2046471358 cites W2081995492 @default.
- W2046471358 cites W2084729080 @default.
- W2046471358 cites W2086201153 @default.
- W2046471358 cites W2086208991 @default.
- W2046471358 cites W2089031168 @default.
- W2046471358 cites W2090933558 @default.
- W2046471358 cites W2092565695 @default.
- W2046471358 cites W2092685021 @default.
- W2046471358 cites W2093178116 @default.
- W2046471358 cites W2094496644 @default.
- W2046471358 cites W2094594116 @default.
- W2046471358 cites W2095684149 @default.
- W2046471358 cites W2096106171 @default.
- W2046471358 cites W2102311939 @default.
- W2046471358 cites W2103001770 @default.
- W2046471358 cites W2104783033 @default.
- W2046471358 cites W2105360146 @default.
- W2046471358 cites W2106380683 @default.
- W2046471358 cites W2108082718 @default.
- W2046471358 cites W2108638666 @default.
- W2046471358 cites W2115146506 @default.
- W2046471358 cites W2116734398 @default.
- W2046471358 cites W2117349535 @default.
- W2046471358 cites W2120030040 @default.
- W2046471358 cites W2121287020 @default.
- W2046471358 cites W2121754812 @default.
- W2046471358 cites W2122843121 @default.
- W2046471358 cites W2124087224 @default.