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• W2046500448 abstract "Scattering parameters and histological properties of the ewe fetal lung microstructure were examined in vitro. Four groups of lamb fetuses were chosen at 80, 100, 130 and 145 days of gestation (10 lambs in all). The acoustic parameters of the lung (backscatter coefficient, integrated backscatter coefficient and effective scatterer size), texture parameter of the lung (effective density of scatterers) and a relative lung/liver maturation parameter (the integrated spectral ratio) were measured at 19 degrees +/- 2 degrees C within the frequency range 3-11 MHz. Values of integrated backscatter coefficient significantly decreased between 80 and 130 days gestation (from -73.0 +/- 5.7 dB to -84.0 +/- 0.9 dB between 3 to 7 MHz and from -70.0 +/- 0.8 dB to -81.3 +/- 0.5 dB between 5 to 11 MHz). Values of the integrated spectral ratio indicate that the echogenicity of the lung is greater than that of the liver. These values also decreased between 80 and 130 days gestation (from 10.5 +/- 1.1 dB to 5.1 +/- 0.9 dB between 3 to 7 MHz and from 10.0 +/- 0.8 dB to -6.4 +/- 0.6 dB between 5 to 11 MHz). Texture analysis showed that the K distribution is a good model to describe the envelope of the backscattered signals from the lung and the values of the effective density of scatterers that decrease between 80 and 130 days. These trends seem to be linked to the maturation of the microstructure of the lung and, particularly, to the development of respiratory terminal structures." @default.
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• W2046500448 date "2001-02-01" @default.
• W2046500448 modified "2023-09-23" @default.
• W2046500448 title "Ultrasonic characterization of maturation of fetal lung microstructure: an animal study" @default.
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• W2046500448 doi "https://doi.org/10.1016/s0301-5629(00)00335-5" @default.
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