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- W2046546107 abstract "The intraperitoneal administration to rats of 500 mg/kg body weight of 2-deoxy-D-glucose, an analog of glucose which produces intracellular glucopenia with rise in extracellular fluid glucose concentration, is followed by a significant though transient reduction of hypothalamic TRH content, observed at 15 and 25 minutes after drug administration. A subsequent increase in serum thyrotropin followed by that of triiodothyronine concentration was also observed. These findings indicate that the neuroglucopenia induced by 2-deoxy-D-glucose may play a role in the regulating the hypothalamic-pituitary-thyroid axis." @default.
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- W2046546107 date "1984-10-01" @default.
- W2046546107 modified "2023-09-27" @default.
- W2046546107 title "Effect of 2-deoxy-D-glucose on hypothalamic-pituitary-thyroid axis in rats" @default.
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- W2046546107 doi "https://doi.org/10.1016/0024-3205(84)90355-2" @default.
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