FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046557478> ?p ?o ?g. }

• W2046557478 endingPage "144" @default.
• W2046557478 startingPage "136" @default.
• W2046557478 abstract "Effects on T lymphocyte mediated pathology, phenotypes, and functions in MRLlpr/lpr mice given mycophenolate mofetil (MMF) (100 mg/kg/day) via drinking water or controls given ip cyclophosphamide (CYC) injections (1.8 mg/mouse/week) or water were described. Both MMF and CYC treatment diminished kidney and large salivary gland perivascular cell infiltrates, reduced profoundly double-negative (DN) T cell frequencies, decreased total lymphocyte number in spleen, and increased in vitro proliferative response to Con A. IFN-gamma and IL-10 in supernatants from Con A stimulated spleen cells were augmented after MMF but not CYC treatment. MMF treatment increased whereas CYC reduced IL-12 in serum. Kidney expressions of IFN-gamma, IL-10, and IL-12 mRNA were unaffected by MMF but decreased by CYC. Our results demonstrate that MMF and CYC suppress perivascular T lymphocyte inflammation by reducing the DN T cell population and by amelioration of T cell function. The varying cytokine patterns suggest different mechanisms of the two drugs." @default.
• W2046557478 created "2016-06-24" @default.
• W2046557478 creator A5022809040 @default.
• W2046557478 creator A5042372370 @default.
• W2046557478 creator A5057578169 @default.
• W2046557478 creator A5075679467 @default.
• W2046557478 creator A5088403071 @default.
• W2046557478 date "1999-11-01" @default.
• W2046557478 modified "2023-10-18" @default.
• W2046557478 title "Mycophenolate Mofetil Ameliorates Perivascular T Lymphocyte Inflammation and Reduces the Double-Negative T Cell Population in SLE-Prone MRLlpr/lpr Mice" @default.
• W2046557478 cites W1487959697 @default.
• W2046557478 cites W1498105805 @default.
• W2046557478 cites W1579399281 @default.
• W2046557478 cites W1580503774 @default.
• W2046557478 cites W1987242751 @default.
• W2046557478 cites W1993632025 @default.
• W2046557478 cites W2014993834 @default.
• W2046557478 cites W2018397075 @default.
• W2046557478 cites W2028111124 @default.
• W2046557478 cites W2037484778 @default.
• W2046557478 cites W2040753895 @default.
• W2046557478 cites W2043349532 @default.
• W2046557478 cites W2044904090 @default.
• W2046557478 cites W2047582352 @default.
• W2046557478 cites W2061744808 @default.
• W2046557478 cites W2063673975 @default.
• W2046557478 cites W2064855387 @default.
• W2046557478 cites W2077594740 @default.
• W2046557478 cites W2077743819 @default.
• W2046557478 cites W2088434842 @default.
• W2046557478 cites W2096265668 @default.
• W2046557478 cites W2096613751 @default.
• W2046557478 cites W2145255000 @default.
• W2046557478 cites W2150064963 @default.
• W2046557478 cites W4313341441 @default.
• W2046557478 cites W1999433842 @default.
• W2046557478 doi "https://doi.org/10.1006/cimm.1999.1570" @default.
• W2046557478 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10607431" @default.
• W2046557478 hasPublicationYear "1999" @default.
• W2046557478 type Work @default.
• W2046557478 sameAs 2046557478 @default.
• W2046557478 citedByCount "47" @default.
• W2046557478 countsByYear W20465574782013 @default.
• W2046557478 countsByYear W20465574782014 @default.
• W2046557478 countsByYear W20465574782015 @default.
• W2046557478 countsByYear W20465574782016 @default.
• W2046557478 countsByYear W20465574782017 @default.
• W2046557478 countsByYear W20465574782018 @default.
• W2046557478 countsByYear W20465574782019 @default.
• W2046557478 countsByYear W20465574782020 @default.
• W2046557478 crossrefType "journal-article" @default.
• W2046557478 hasAuthorship W2046557478A5022809040 @default.
• W2046557478 hasAuthorship W2046557478A5042372370 @default.
• W2046557478 hasAuthorship W2046557478A5057578169 @default.
• W2046557478 hasAuthorship W2046557478A5075679467 @default.
• W2046557478 hasAuthorship W2046557478A5088403071 @default.
• W2046557478 hasConcept C126322002 @default.
• W2046557478 hasConcept C134018914 @default.
• W2046557478 hasConcept C203014093 @default.
• W2046557478 hasConcept C2776090121 @default.
• W2046557478 hasConcept C2776694085 @default.
• W2046557478 hasConcept C2776755627 @default.
• W2046557478 hasConcept C2776914184 @default.
• W2046557478 hasConcept C2777761686 @default.
• W2046557478 hasConcept C2778690821 @default.
• W2046557478 hasConcept C2778740727 @default.
• W2046557478 hasConcept C2780091579 @default.
• W2046557478 hasConcept C2780841837 @default.
• W2046557478 hasConcept C2780931953 @default.
• W2046557478 hasConcept C2908647359 @default.
• W2046557478 hasConcept C2909935303 @default.
• W2046557478 hasConcept C2911091166 @default.
• W2046557478 hasConcept C2992881475 @default.
• W2046557478 hasConcept C71924100 @default.
• W2046557478 hasConcept C86803240 @default.
• W2046557478 hasConcept C8891405 @default.
• W2046557478 hasConcept C99454951 @default.
• W2046557478 hasConceptScore W2046557478C126322002 @default.
• W2046557478 hasConceptScore W2046557478C134018914 @default.
• W2046557478 hasConceptScore W2046557478C203014093 @default.
• W2046557478 hasConceptScore W2046557478C2776090121 @default.
• W2046557478 hasConceptScore W2046557478C2776694085 @default.
• W2046557478 hasConceptScore W2046557478C2776755627 @default.
• W2046557478 hasConceptScore W2046557478C2776914184 @default.
• W2046557478 hasConceptScore W2046557478C2777761686 @default.
• W2046557478 hasConceptScore W2046557478C2778690821 @default.
• W2046557478 hasConceptScore W2046557478C2778740727 @default.
• W2046557478 hasConceptScore W2046557478C2780091579 @default.
• W2046557478 hasConceptScore W2046557478C2780841837 @default.
• W2046557478 hasConceptScore W2046557478C2780931953 @default.
• W2046557478 hasConceptScore W2046557478C2908647359 @default.
• W2046557478 hasConceptScore W2046557478C2909935303 @default.
• W2046557478 hasConceptScore W2046557478C2911091166 @default.
• W2046557478 hasConceptScore W2046557478C2992881475 @default.
• W2046557478 hasConceptScore W2046557478C71924100 @default.
• W2046557478 hasConceptScore W2046557478C86803240 @default.
• W2046557478 hasConceptScore W2046557478C8891405 @default.
• W2046557478 hasConceptScore W2046557478C99454951 @default.

• next