FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046603905> ?p ?o ?g. }

• W2046603905 endingPage "197" @default.
• W2046603905 startingPage "190" @default.
• W2046603905 abstract "To assess the time course of increases in N-acetyl-aspartate/creatine (NAA/Cr), which can be measured using proton MR spectroscopic imaging (1H-MRSI), in patients with intractable nonlesional temporal lobe epilepsy (TLE) after successful epilepsy surgery.We performed pre- and postoperative 1H-MRSI in 16 seizure-free (SF) patients and 16 not seizure-free (NSF) TLE patients. We calculated a mixed-design analysis of variance (ANOVA) between SF and NSF groups, ipsi- and contralateral to the side of operation, and pre- and postoperative NAA/Cr measurements. We applied nonlinear regression between pre- and postoperative NAA/Cr differences and the time interval between 1H-MRSI scans to fit a negative exponential model to NAA recovery.Mixed-design ANOVA revealed that (a) postoperative NAA/Cr was significantly higher in SF than in NSF patients (p = 0.02) and that (b) in the SF group, postoperative NAA/Cr values were significantly higher than preoperative values (p < 0.05) and returned to the normal range in most patients. According to our nonlinear regression model, in SF patients, there was a 50% increase relative to preoperative NAA/Cr values after 5.8 months, whereas an improvement of 95% was reached after 25 months.Our results extend preliminary observations of postoperative NAA recovery of SF patients by characterizing the time course of recovery as an exponential function with a half-time of approximately 6 months. The reversal of neuronal metabolic dysfunction remote from the epileptic focus may underlie the clinical observation of improvement of cognitive dysfunction after successful epilepsy surgery." @default.
• W2046603905 created "2016-06-24" @default.
• W2046603905 creator A5006679597 @default.
• W2046603905 creator A5008170944 @default.
• W2046603905 creator A5020040805 @default.
• W2046603905 creator A5022841763 @default.
• W2046603905 creator A5033957465 @default.
• W2046603905 creator A5044809264 @default.
• W2046603905 creator A5044839435 @default.
• W2046603905 creator A5053040162 @default.
• W2046603905 creator A5065754098 @default.
• W2046603905 date "2008-10-09" @default.
• W2046603905 modified "2023-09-28" @default.
• W2046603905 title "Time Course of Postoperative Recovery of N-Acetyl-Aspartate in Temporal Lobe Epilepsy" @default.
• W2046603905 cites W1977336425 @default.
• W2046603905 cites W1979612418 @default.
• W2046603905 cites W1984066695 @default.
• W2046603905 cites W2006283660 @default.
• W2046603905 cites W2006355389 @default.
• W2046603905 cites W2008991090 @default.
• W2046603905 cites W2027290785 @default.
• W2046603905 cites W2027833778 @default.
• W2046603905 cites W2056460051 @default.
• W2046603905 cites W2063431778 @default.
• W2046603905 cites W2067856703 @default.
• W2046603905 cites W2068645410 @default.
• W2046603905 cites W2078962795 @default.
• W2046603905 cites W2083082730 @default.
• W2046603905 cites W2085417640 @default.
• W2046603905 cites W2088388877 @default.
• W2046603905 cites W2103376251 @default.
• W2046603905 cites W2118129131 @default.
• W2046603905 cites W2133006254 @default.
• W2046603905 cites W2136743000 @default.
• W2046603905 cites W2155941672 @default.
• W2046603905 cites W2160560005 @default.
• W2046603905 cites W2160760539 @default.
• W2046603905 cites W2161351145 @default.
• W2046603905 cites W2164255848 @default.
• W2046603905 cites W4297162325 @default.
• W2046603905 doi "https://doi.org/10.1046/j.1528-1157.2001.01300.x" @default.
• W2046603905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11240588" @default.
• W2046603905 hasPublicationYear "2008" @default.
• W2046603905 type Work @default.
• W2046603905 sameAs 2046603905 @default.
• W2046603905 citedByCount "30" @default.
• W2046603905 countsByYear W20466039052012 @default.
• W2046603905 countsByYear W20466039052013 @default.
• W2046603905 countsByYear W20466039052016 @default.
• W2046603905 countsByYear W20466039052019 @default.
• W2046603905 countsByYear W20466039052023 @default.
• W2046603905 crossrefType "journal-article" @default.
• W2046603905 hasAuthorship W2046603905A5006679597 @default.
• W2046603905 hasAuthorship W2046603905A5008170944 @default.
• W2046603905 hasAuthorship W2046603905A5020040805 @default.
• W2046603905 hasAuthorship W2046603905A5022841763 @default.
• W2046603905 hasAuthorship W2046603905A5033957465 @default.
• W2046603905 hasAuthorship W2046603905A5044809264 @default.
• W2046603905 hasAuthorship W2046603905A5044839435 @default.
• W2046603905 hasAuthorship W2046603905A5053040162 @default.
• W2046603905 hasAuthorship W2046603905A5065754098 @default.
• W2046603905 hasConcept C102959455 @default.
• W2046603905 hasConcept C105795698 @default.
• W2046603905 hasConcept C126322002 @default.
• W2046603905 hasConcept C141071460 @default.
• W2046603905 hasConcept C15744967 @default.
• W2046603905 hasConcept C169760540 @default.
• W2046603905 hasConcept C2778186239 @default.
• W2046603905 hasConcept C2779896295 @default.
• W2046603905 hasConcept C2780803581 @default.
• W2046603905 hasConcept C2781099131 @default.
• W2046603905 hasConcept C2989005 @default.
• W2046603905 hasConcept C33923547 @default.
• W2046603905 hasConcept C42219234 @default.
• W2046603905 hasConcept C71924100 @default.
• W2046603905 hasConcept C99476002 @default.
• W2046603905 hasConceptScore W2046603905C102959455 @default.
• W2046603905 hasConceptScore W2046603905C105795698 @default.
• W2046603905 hasConceptScore W2046603905C126322002 @default.
• W2046603905 hasConceptScore W2046603905C141071460 @default.
• W2046603905 hasConceptScore W2046603905C15744967 @default.
• W2046603905 hasConceptScore W2046603905C169760540 @default.
• W2046603905 hasConceptScore W2046603905C2778186239 @default.
• W2046603905 hasConceptScore W2046603905C2779896295 @default.
• W2046603905 hasConceptScore W2046603905C2780803581 @default.
• W2046603905 hasConceptScore W2046603905C2781099131 @default.
• W2046603905 hasConceptScore W2046603905C2989005 @default.
• W2046603905 hasConceptScore W2046603905C33923547 @default.
• W2046603905 hasConceptScore W2046603905C42219234 @default.
• W2046603905 hasConceptScore W2046603905C71924100 @default.
• W2046603905 hasConceptScore W2046603905C99476002 @default.
• W2046603905 hasIssue "2" @default.
• W2046603905 hasLocation W20466039051 @default.
• W2046603905 hasLocation W20466039052 @default.
• W2046603905 hasOpenAccess W2046603905 @default.
• W2046603905 hasPrimaryLocation W20466039051 @default.
• W2046603905 hasRelatedWork W131628292 @default.
• W2046603905 hasRelatedWork W1978120509 @default.

• next