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- W2046665438 abstract "The vacuolating cytotoxin VacA, a polypeptide of about 88 kDa, is one of the major virulence factors of Helicobacter pylori. VacA essentially acts as an invasive chloride channel targeting mitochondria. The results of recent studies open a new perspective on the mechanisms by which VacA causes loss of the mitochondrial membrane potential, mitochondrial fragmentation, formation of reactive oxygen species, autophagy, cell death and gastric cancer." @default.
- W2046665438 created "2016-06-24" @default.
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- W2046665438 date "2012-10-01" @default.
- W2046665438 modified "2023-10-18" @default.
- W2046665438 title "Helicobacter pylori VacA: a new perspective on an invasive chloride channel" @default.
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- W2046665438 doi "https://doi.org/10.1016/j.micinf.2012.07.002" @default.
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