FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046670265> ?p ?o ?g. }

• W2046670265 endingPage "3066" @default.
• W2046670265 startingPage "3057" @default.
• W2046670265 abstract "In silico studies carried out by using a computer model of oxidative phosphorylation and anaerobic glycolysis in skeletal muscle demonstrated that deamination of AMP to IMP during heavy short term exercise and/or hypoxia lessens the acidification of myocytes. The concerted action of adenylate kinase and AMP deaminase, leading to a decrease in the total adenine nucleotide pool, constitutes an additional process consuming ADP and producing ATP. It diminishes the amount of ADP that must be converted to ATP by other processes in order to meet the rate of ADP production by ATPases (because the adenylate kinase + AMP deaminase system produces only 1 ATP per 2 ADPs used, ATP consumption is not matched by ATP production, and the reduction of the total adenine nucleotide pool occurs mostly at the cost of [ATP]). As a result, the rate of ADP consumption by other processes may be lowered. This effect concerns mostly ADP consumption by anaerobic glycolysis that is inhibited by AMP deamination-induced decrease in [ADP] and [AMP], and not oxidative phosphorylation, because during heavy exercise and/or hypoxia [ADP] is significantly greater than the Km value of this process for ADP. The resultant reduction of proton production by anaerobic glycolysis enables us to delay the termination of exercise because of fatigue and/or to diminish cell damage." @default.
• W2046670265 created "2016-06-24" @default.
• W2046670265 creator A5060487324 @default.
• W2046670265 date "2006-02-01" @default.
• W2046670265 modified "2023-09-26" @default.
• W2046670265 title "AMP Deamination Delays Muscle Acidification during Heavy Exercise and Hypoxia" @default.
• W2046670265 cites W1535644751 @default.
• W2046670265 cites W1978495288 @default.
• W2046670265 cites W1978993618 @default.
• W2046670265 cites W1985114762 @default.
• W2046670265 cites W1999642683 @default.
• W2046670265 cites W1999840377 @default.
• W2046670265 cites W2000450781 @default.
• W2046670265 cites W2006934277 @default.
• W2046670265 cites W2013820501 @default.
• W2046670265 cites W2014272583 @default.
• W2046670265 cites W2026815584 @default.
• W2046670265 cites W2028011301 @default.
• W2046670265 cites W2034854942 @default.
• W2046670265 cites W2036577693 @default.
• W2046670265 cites W2039405238 @default.
• W2046670265 cites W2048408738 @default.
• W2046670265 cites W2054414250 @default.
• W2046670265 cites W2058929419 @default.
• W2046670265 cites W2063590495 @default.
• W2046670265 cites W2083819076 @default.
• W2046670265 cites W2084249132 @default.
• W2046670265 cites W2091591758 @default.
• W2046670265 cites W2104375676 @default.
• W2046670265 cites W2114293440 @default.
• W2046670265 cites W2146665077 @default.
• W2046670265 cites W2146955177 @default.
• W2046670265 cites W2161912843 @default.
• W2046670265 cites W2167376898 @default.
• W2046670265 cites W2181321811 @default.
• W2046670265 cites W2188618846 @default.
• W2046670265 cites W2254445197 @default.
• W2046670265 cites W2276904486 @default.
• W2046670265 cites W2278101261 @default.
• W2046670265 cites W2290495595 @default.
• W2046670265 cites W2292685468 @default.
• W2046670265 cites W2338771681 @default.
• W2046670265 cites W2339163018 @default.
• W2046670265 doi "https://doi.org/10.1074/jbc.m510418200" @default.
• W2046670265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16314416" @default.
• W2046670265 hasPublicationYear "2006" @default.
• W2046670265 type Work @default.
• W2046670265 sameAs 2046670265 @default.
• W2046670265 citedByCount "36" @default.
• W2046670265 countsByYear W20466702652012 @default.
• W2046670265 countsByYear W20466702652013 @default.
• W2046670265 countsByYear W20466702652014 @default.
• W2046670265 countsByYear W20466702652015 @default.
• W2046670265 countsByYear W20466702652017 @default.
• W2046670265 countsByYear W20466702652018 @default.
• W2046670265 countsByYear W20466702652019 @default.
• W2046670265 countsByYear W20466702652020 @default.
• W2046670265 countsByYear W20466702652021 @default.
• W2046670265 countsByYear W20466702652022 @default.
• W2046670265 crossrefType "journal-article" @default.
• W2046670265 hasAuthorship W2046670265A5060487324 @default.
• W2046670265 hasBestOaLocation W20466702651 @default.
• W2046670265 hasConcept C104317684 @default.
• W2046670265 hasConcept C145782189 @default.
• W2046670265 hasConcept C165912504 @default.
• W2046670265 hasConcept C178790620 @default.
• W2046670265 hasConcept C180526460 @default.
• W2046670265 hasConcept C181199279 @default.
• W2046670265 hasConcept C185592680 @default.
• W2046670265 hasConcept C20251656 @default.
• W2046670265 hasConcept C23265538 @default.
• W2046670265 hasConcept C2779564974 @default.
• W2046670265 hasConcept C2994266630 @default.
• W2046670265 hasConcept C34628245 @default.
• W2046670265 hasConcept C42407357 @default.
• W2046670265 hasConcept C512185932 @default.
• W2046670265 hasConcept C5140985 @default.
• W2046670265 hasConcept C540031477 @default.
• W2046670265 hasConcept C55493867 @default.
• W2046670265 hasConcept C55885012 @default.
• W2046670265 hasConcept C57600042 @default.
• W2046670265 hasConcept C62231903 @default.
• W2046670265 hasConcept C7836513 @default.
• W2046670265 hasConcept C86803240 @default.
• W2046670265 hasConceptScore W2046670265C104317684 @default.
• W2046670265 hasConceptScore W2046670265C145782189 @default.
• W2046670265 hasConceptScore W2046670265C165912504 @default.
• W2046670265 hasConceptScore W2046670265C178790620 @default.
• W2046670265 hasConceptScore W2046670265C180526460 @default.
• W2046670265 hasConceptScore W2046670265C181199279 @default.
• W2046670265 hasConceptScore W2046670265C185592680 @default.
• W2046670265 hasConceptScore W2046670265C20251656 @default.
• W2046670265 hasConceptScore W2046670265C23265538 @default.
• W2046670265 hasConceptScore W2046670265C2779564974 @default.
• W2046670265 hasConceptScore W2046670265C2994266630 @default.
• W2046670265 hasConceptScore W2046670265C34628245 @default.
• W2046670265 hasConceptScore W2046670265C42407357 @default.
• W2046670265 hasConceptScore W2046670265C512185932 @default.

• next