FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046875603> ?p ?o ?g. }

• W2046875603 abstract "All multi-cellular living organisms are very complex microfluidics systems, which are assembled 'inside-out', as the result of a complex 'tug-of-war' process comprising both feed-forward modules, in particular the program embedded in the species' DNA, and feed-back processes, in particular the response to external environmental conditions. Living organisms have to solve a perennial problem: for an environment with limited resources (finite and spatial distribution of nutrients, geometrical limitations, competition from other species, etc.), finite growth rate and penalties applied to nonoptimal behaviour, what is the best strategy that will maximise growth and survival of the individual and the species? Identifying how organisms resolve this problem is very difficult due to the high complexity involved. However, filamentous fungi and other simple organisms, provide a means to address these issues due to the availability of microscopic imaging and microfabricated geometries in which the behaviour can be tested. Semiconductor fabrication (photolithography, RIE etching, and soft lithography techniques) was used here to produce artificial micro-networks, which are physically and chemically structured 3D microenvironments. Continuous imaging of fungal behaviour in microfluidics networks required the use of PDMS, which is transparent and O₂-permeable. Using these structures, the dynamic growth behaviour of two fungal species <i>Neurospora crassa </i>and <i>Armillaria mellea</i> was observed microscopically in real-time. Growth parameters such as the tip extension velocities, branching angles and branching distances on plain surfaces differed vastly between the species. Features in the micronetworks of a size similar to the hyphal diameter induced the largest change in growth parameters such as, the largest decrease in branching distances in N. crassa and a near complete suppression for <i>A. mellea</i>. Despite these fundamental differences, both species negotiated the structures successfully. These results open the way to asking more fundamental questions, such as which species use algorithms that are most efficient for solving a particular type of mathematical problem coded in a network? Can these natural algorithms be used for either better control of fungal growth and metabolism for both medical and biotechnology applications; or even for new computation paradigms?" @default.
• W2046875603 created "2016-06-24" @default.
• W2046875603 creator A5028338973 @default.
• W2046875603 creator A5034889819 @default.
• W2046875603 creator A5043698287 @default.
• W2046875603 creator A5073159119 @default.
• W2046875603 date "2009-02-12" @default.
• W2046875603 modified "2023-09-23" @default.
• W2046875603 title "Dynamic behaviour of fungi in microfluidics: a comparative study" @default.
• W2046875603 doi "https://doi.org/10.1117/12.822464" @default.
• W2046875603 hasPublicationYear "2009" @default.
• W2046875603 type Work @default.
• W2046875603 sameAs 2046875603 @default.
• W2046875603 citedByCount "5" @default.
• W2046875603 countsByYear W20468756032018 @default.
• W2046875603 countsByYear W20468756032020 @default.
• W2046875603 countsByYear W20468756032021 @default.
• W2046875603 countsByYear W20468756032022 @default.
• W2046875603 crossrefType "proceedings-article" @default.
• W2046875603 hasAuthorship W2046875603A5028338973 @default.
• W2046875603 hasAuthorship W2046875603A5034889819 @default.
• W2046875603 hasAuthorship W2046875603A5043698287 @default.
• W2046875603 hasAuthorship W2046875603A5073159119 @default.
• W2046875603 hasConcept C105487726 @default.
• W2046875603 hasConcept C168197293 @default.
• W2046875603 hasConcept C171250308 @default.
• W2046875603 hasConcept C186060115 @default.
• W2046875603 hasConcept C187937830 @default.
• W2046875603 hasConcept C18903297 @default.
• W2046875603 hasConcept C192562407 @default.
• W2046875603 hasConcept C204223013 @default.
• W2046875603 hasConcept C2777407749 @default.
• W2046875603 hasConcept C2780618852 @default.
• W2046875603 hasConcept C34069715 @default.
• W2046875603 hasConcept C41008148 @default.
• W2046875603 hasConcept C49040817 @default.
• W2046875603 hasConcept C8673954 @default.
• W2046875603 hasConcept C86803240 @default.
• W2046875603 hasConceptScore W2046875603C105487726 @default.
• W2046875603 hasConceptScore W2046875603C168197293 @default.
• W2046875603 hasConceptScore W2046875603C171250308 @default.
• W2046875603 hasConceptScore W2046875603C186060115 @default.
• W2046875603 hasConceptScore W2046875603C187937830 @default.
• W2046875603 hasConceptScore W2046875603C18903297 @default.
• W2046875603 hasConceptScore W2046875603C192562407 @default.
• W2046875603 hasConceptScore W2046875603C204223013 @default.
• W2046875603 hasConceptScore W2046875603C2777407749 @default.
• W2046875603 hasConceptScore W2046875603C2780618852 @default.
• W2046875603 hasConceptScore W2046875603C34069715 @default.
• W2046875603 hasConceptScore W2046875603C41008148 @default.
• W2046875603 hasConceptScore W2046875603C49040817 @default.
• W2046875603 hasConceptScore W2046875603C8673954 @default.
• W2046875603 hasConceptScore W2046875603C86803240 @default.
• W2046875603 hasLocation W20468756031 @default.
• W2046875603 hasOpenAccess W2046875603 @default.
• W2046875603 hasPrimaryLocation W20468756031 @default.
• W2046875603 hasRelatedWork W1974416320 @default.
• W2046875603 hasRelatedWork W2002873055 @default.
• W2046875603 hasRelatedWork W2020632979 @default.
• W2046875603 hasRelatedWork W2021077848 @default.
• W2046875603 hasRelatedWork W2078782272 @default.
• W2046875603 hasRelatedWork W2079029947 @default.
• W2046875603 hasRelatedWork W2971340477 @default.
• W2046875603 hasRelatedWork W3099064366 @default.
• W2046875603 hasRelatedWork W3217260345 @default.
• W2046875603 hasRelatedWork W647569634 @default.
• W2046875603 isParatext "false" @default.
• W2046875603 isRetracted "false" @default.
• W2046875603 magId "2046875603" @default.
• W2046875603 workType "article" @default.