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- W2046906732 abstract "To assess the combination of endometrial thickness as measured by transvaginal sonography and time since menopause in predicting endometrial cancer in women with postmenopausal bleeding. The study group included 95 women with postmenopausal bleeding who underwent sonographic measurement of the endometrial thickness followed by endometrial biopsy. None of the patients included had ever used hormone replacement therapy. The mean endometrial thickness was significantly lower in the absense of endometrial carcinoma (6.9 ± 4.3 mm) than in its presence (13.5 ± 7.7 mm) (p < 0.005). The incidence of endometrial carcinoma increased with the increases in endometrial thickness and the number of years since menopause. No patient had carcinoma when the endometrium was less than 5 mm thick but 18.5% did when the endometrium exceeded 9 mm. The incidence of cancer was 2.6% in women who had undergone menopause less than 5 years earlier but was 21.4% in women more than 15 years since menopause multiple logistic regression analysis showed that time since menopause and endometrial thickness were statistically significant predictors of endometrial carcinoma. time since menopause and endometrial thickness together define cutoff points for the diagnostic biopsy for endometrial carcinoma; that is, within a particular time interval, sampling should not be performed if the thickness is below a given value. When using cutoff points of 6 mm endometrial thickness for women experiencing menopause 5–15 years prior and 5 mm in those 15 or more years since menopause, approximately 60% of invasive procedures may be avoided. Such models can also be used to calculate a patient's risk of cancer based on her age and endometrial thickness." @default.
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- W2046906732 date "2004-08-01" @default.
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- W2046906732 title "P06.12: Combination of endometrial thickness and time since menopause in predicting endometrial cancer in women with postmenopausal bleeding" @default.
- W2046906732 doi "https://doi.org/10.1002/uog.1444" @default.
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