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- W2046918087 abstract "ABSTRACT An efficient methodology for regiospecific glycosylation was developed by using 6-O-tert-butyldiphenylsilyl N-acetylglucosamine derivatives 3 and 5 which bear two free hydroxyl groups as acceptors. The regiospecificity was attributed to the presence of the tert-butyldiphenylsilyl group at the O-6 position of the N-acetylglucosamine derivatives. Glycosylation of suitably protected galactoside donors 10-14 with acceptors 3 and 5 gave only β (1→4) linked disaccharides 15-19 in good yields. Fucosylation of disaccharide 18 led to Lewis X (Lex) trisaccharide 21 in high yield." @default.
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- W2046918087 date "1999-01-01" @default.
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- W2046918087 title "Regiospecific Syntheses of <i>N</i>-Acetyllactosamine Derivatives and Application Toward a Highly Practical Synthesis of Lewis X Trisaccharide" @default.
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- W2046918087 doi "https://doi.org/10.1080/07328309908544034" @default.
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