Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046921710> ?p ?o ?g. }
- W2046921710 endingPage "1078" @default.
- W2046921710 startingPage "1067" @default.
- W2046921710 abstract "The operation of the mammalian cochlea relies on a mechanical traveling wave that is actively boosted by electromechanical forces in sensory outer hair cells (OHCs). This active cochlear amplifier produces the impressive sensitivity and frequency resolution of mammalian hearing. The cochlear amplifier has inspired scientists since its discovery in the 1970s, and is still not well understood. To explore cochlear electromechanics at the sensory cell/tissue interface, sound-evoked intracochlear pressure and extracellular voltage were measured using a recently developed dual-sensor with a microelectrode attached to a micro-pressure sensor. The resulting coincident in vivo observations of OHC electrical activity, pressure at the basilar membrane and basilar membrane displacement gave direct evidence for power amplification in the cochlea. Moreover, the results showed a phase shift of voltage relative to mechanical responses at frequencies slightly below the peak, near the onset of amplification. Based on the voltage-force relationship of isolated OHCs, the shift would give rise to effective OHC pumping forces within the traveling wave peak. Thus, the shift activates the cochlear amplifier, serving to localize and thus sharpen the frequency region of amplification. These results are the most concrete evidence for cochlear power amplification to date and support OHC somatic forces as its source." @default.
- W2046921710 created "2016-06-24" @default.
- W2046921710 creator A5030833877 @default.
- W2046921710 creator A5054682248 @default.
- W2046921710 date "2013-08-01" @default.
- W2046921710 modified "2023-10-14" @default.
- W2046921710 title "Detection of Cochlear Amplification and Its Activation" @default.
- W2046921710 cites W1661238664 @default.
- W2046921710 cites W1964532154 @default.
- W2046921710 cites W1968720037 @default.
- W2046921710 cites W1969250228 @default.
- W2046921710 cites W1970156599 @default.
- W2046921710 cites W1985457532 @default.
- W2046921710 cites W1987557467 @default.
- W2046921710 cites W1989902389 @default.
- W2046921710 cites W1993277788 @default.
- W2046921710 cites W1997831837 @default.
- W2046921710 cites W2002134957 @default.
- W2046921710 cites W2005887793 @default.
- W2046921710 cites W2008340178 @default.
- W2046921710 cites W2009262552 @default.
- W2046921710 cites W2018408627 @default.
- W2046921710 cites W2018729336 @default.
- W2046921710 cites W2020991261 @default.
- W2046921710 cites W2024788304 @default.
- W2046921710 cites W2030026764 @default.
- W2046921710 cites W2030882845 @default.
- W2046921710 cites W2035558883 @default.
- W2046921710 cites W2036788442 @default.
- W2046921710 cites W2039130308 @default.
- W2046921710 cites W2044441118 @default.
- W2046921710 cites W2046942711 @default.
- W2046921710 cites W2048825739 @default.
- W2046921710 cites W2050677366 @default.
- W2046921710 cites W2053351827 @default.
- W2046921710 cites W2054199156 @default.
- W2046921710 cites W2056239356 @default.
- W2046921710 cites W2057554140 @default.
- W2046921710 cites W2061038984 @default.
- W2046921710 cites W2064022796 @default.
- W2046921710 cites W2068435148 @default.
- W2046921710 cites W2075437668 @default.
- W2046921710 cites W2076082657 @default.
- W2046921710 cites W2111585246 @default.
- W2046921710 cites W2140061722 @default.
- W2046921710 cites W2147635856 @default.
- W2046921710 cites W2335258120 @default.
- W2046921710 cites W4230460901 @default.
- W2046921710 cites W4249471170 @default.
- W2046921710 cites W4366658009 @default.
- W2046921710 doi "https://doi.org/10.1016/j.bpj.2013.06.049" @default.
- W2046921710 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3752116" @default.
- W2046921710 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23972858" @default.
- W2046921710 hasPublicationYear "2013" @default.
- W2046921710 type Work @default.
- W2046921710 sameAs 2046921710 @default.
- W2046921710 citedByCount "111" @default.
- W2046921710 countsByYear W20469217102013 @default.
- W2046921710 countsByYear W20469217102014 @default.
- W2046921710 countsByYear W20469217102015 @default.
- W2046921710 countsByYear W20469217102016 @default.
- W2046921710 countsByYear W20469217102017 @default.
- W2046921710 countsByYear W20469217102018 @default.
- W2046921710 countsByYear W20469217102019 @default.
- W2046921710 countsByYear W20469217102020 @default.
- W2046921710 countsByYear W20469217102021 @default.
- W2046921710 countsByYear W20469217102022 @default.
- W2046921710 countsByYear W20469217102023 @default.
- W2046921710 crossrefType "journal-article" @default.
- W2046921710 hasAuthorship W2046921710A5030833877 @default.
- W2046921710 hasAuthorship W2046921710A5054682248 @default.
- W2046921710 hasBestOaLocation W20469217101 @default.
- W2046921710 hasConcept C105702510 @default.
- W2046921710 hasConcept C121332964 @default.
- W2046921710 hasConcept C12554922 @default.
- W2046921710 hasConcept C136229726 @default.
- W2046921710 hasConcept C185592680 @default.
- W2046921710 hasConcept C192562407 @default.
- W2046921710 hasConcept C194257627 @default.
- W2046921710 hasConcept C24890656 @default.
- W2046921710 hasConcept C2778500370 @default.
- W2046921710 hasConcept C2780130748 @default.
- W2046921710 hasConcept C2780807236 @default.
- W2046921710 hasConcept C46362747 @default.
- W2046921710 hasConcept C49040817 @default.
- W2046921710 hasConcept C68115822 @default.
- W2046921710 hasConcept C71924100 @default.
- W2046921710 hasConcept C86803240 @default.
- W2046921710 hasConceptScore W2046921710C105702510 @default.
- W2046921710 hasConceptScore W2046921710C121332964 @default.
- W2046921710 hasConceptScore W2046921710C12554922 @default.
- W2046921710 hasConceptScore W2046921710C136229726 @default.
- W2046921710 hasConceptScore W2046921710C185592680 @default.
- W2046921710 hasConceptScore W2046921710C192562407 @default.
- W2046921710 hasConceptScore W2046921710C194257627 @default.
- W2046921710 hasConceptScore W2046921710C24890656 @default.
- W2046921710 hasConceptScore W2046921710C2778500370 @default.
- W2046921710 hasConceptScore W2046921710C2780130748 @default.