Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046925327> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2046925327 endingPage "13" @default.
- W2046925327 startingPage "1" @default.
- W2046925327 abstract "The simultaneous determination of some hydroxycholesterols in human serum samples is described. The procedure is based on hydrolysis and extraction of these compounds in serum samples, followed by removal of especially cholesterol (making use of reversed-phase high-performance liquid chromatography) and derivatization of the purified compounds to their trimethylsilyl ethers and subsequent gas chromatography using flame ionization detection. Serum levels of 7α-hydroxycholesterol, 7β-hydroxycholesterol and 26-hydroxycholesterol were determined in several groups of patients: (a) normals, (b) untreated patients suffering from cerebrotendinous xanthomatoais, (c) patients suffering from cerebrotendinous xanthomatosis and treated with either chenodeoxycholic acid or cholic acid in an effective dose, (d) patients suffering from cerebro-hepato-renal syndrome, (e) patients suffering from hypercholesterolemia and treated with cholestyramine for prolonged periods and (f) one patient presumed to be suffering from an inborn error of metabolism in bile acid synthesis. It can be concluded that the 7α-hydyroxycholesterol concentration in serum is a good parameter for establishing disorders involving the metabolic conversion of 7α-hydroxycholesterol towards bile acids. In addition, 26-hydroxycholesterol levels in patients suffering from cerebrotendinous xanthomatosis are beyond detectable limits, even during treatment with bile acids in an effective dose, whereas in all other conditions this compound is substantially present." @default.
- W2046925327 created "2016-06-24" @default.
- W2046925327 creator A5003237450 @default.
- W2046925327 creator A5020402992 @default.
- W2046925327 creator A5055000358 @default.
- W2046925327 creator A5084394731 @default.
- W2046925327 date "1987-01-01" @default.
- W2046925327 modified "2023-09-25" @default.
- W2046925327 title "Determination of some hydroxycholesterols in human serum samples" @default.
- W2046925327 cites W1597768999 @default.
- W2046925327 cites W1879718453 @default.
- W2046925327 cites W1988188471 @default.
- W2046925327 cites W1996127538 @default.
- W2046925327 cites W2002275359 @default.
- W2046925327 cites W2004475409 @default.
- W2046925327 cites W2010582484 @default.
- W2046925327 cites W2044988230 @default.
- W2046925327 cites W2052987742 @default.
- W2046925327 cites W2081730973 @default.
- W2046925327 cites W2081773555 @default.
- W2046925327 cites W2088435596 @default.
- W2046925327 cites W2276291647 @default.
- W2046925327 cites W2310361929 @default.
- W2046925327 cites W2319464753 @default.
- W2046925327 cites W2344388674 @default.
- W2046925327 cites W2397797320 @default.
- W2046925327 cites W2409489705 @default.
- W2046925327 doi "https://doi.org/10.1016/0378-4347(87)80479-6" @default.
- W2046925327 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3597624" @default.
- W2046925327 hasPublicationYear "1987" @default.
- W2046925327 type Work @default.
- W2046925327 sameAs 2046925327 @default.
- W2046925327 citedByCount "64" @default.
- W2046925327 countsByYear W20469253272012 @default.
- W2046925327 countsByYear W20469253272014 @default.
- W2046925327 countsByYear W20469253272016 @default.
- W2046925327 crossrefType "journal-article" @default.
- W2046925327 hasAuthorship W2046925327A5003237450 @default.
- W2046925327 hasAuthorship W2046925327A5020402992 @default.
- W2046925327 hasAuthorship W2046925327A5055000358 @default.
- W2046925327 hasAuthorship W2046925327A5084394731 @default.
- W2046925327 hasConcept C126322002 @default.
- W2046925327 hasConcept C134018914 @default.
- W2046925327 hasConcept C179998833 @default.
- W2046925327 hasConcept C185592680 @default.
- W2046925327 hasConcept C2775900799 @default.
- W2046925327 hasConcept C2776923573 @default.
- W2046925327 hasConcept C2778163477 @default.
- W2046925327 hasConcept C2778697171 @default.
- W2046925327 hasConcept C2779399885 @default.
- W2046925327 hasConcept C2780965833 @default.
- W2046925327 hasConcept C2781089062 @default.
- W2046925327 hasConcept C2909350188 @default.
- W2046925327 hasConcept C43617362 @default.
- W2046925327 hasConcept C55493867 @default.
- W2046925327 hasConcept C71924100 @default.
- W2046925327 hasConcept C94412978 @default.
- W2046925327 hasConceptScore W2046925327C126322002 @default.
- W2046925327 hasConceptScore W2046925327C134018914 @default.
- W2046925327 hasConceptScore W2046925327C179998833 @default.
- W2046925327 hasConceptScore W2046925327C185592680 @default.
- W2046925327 hasConceptScore W2046925327C2775900799 @default.
- W2046925327 hasConceptScore W2046925327C2776923573 @default.
- W2046925327 hasConceptScore W2046925327C2778163477 @default.
- W2046925327 hasConceptScore W2046925327C2778697171 @default.
- W2046925327 hasConceptScore W2046925327C2779399885 @default.
- W2046925327 hasConceptScore W2046925327C2780965833 @default.
- W2046925327 hasConceptScore W2046925327C2781089062 @default.
- W2046925327 hasConceptScore W2046925327C2909350188 @default.
- W2046925327 hasConceptScore W2046925327C43617362 @default.
- W2046925327 hasConceptScore W2046925327C55493867 @default.
- W2046925327 hasConceptScore W2046925327C71924100 @default.
- W2046925327 hasConceptScore W2046925327C94412978 @default.
- W2046925327 hasLocation W20469253271 @default.
- W2046925327 hasLocation W20469253272 @default.
- W2046925327 hasOpenAccess W2046925327 @default.
- W2046925327 hasPrimaryLocation W20469253271 @default.
- W2046925327 hasRelatedWork W1486286511 @default.
- W2046925327 hasRelatedWork W1569714421 @default.
- W2046925327 hasRelatedWork W1972390532 @default.
- W2046925327 hasRelatedWork W2015170778 @default.
- W2046925327 hasRelatedWork W2046925327 @default.
- W2046925327 hasRelatedWork W2068634846 @default.
- W2046925327 hasRelatedWork W2076678916 @default.
- W2046925327 hasRelatedWork W2077886405 @default.
- W2046925327 hasRelatedWork W2081773555 @default.
- W2046925327 hasRelatedWork W4235546563 @default.
- W2046925327 hasVolume "416" @default.
- W2046925327 isParatext "false" @default.
- W2046925327 isRetracted "false" @default.
- W2046925327 magId "2046925327" @default.
- W2046925327 workType "article" @default.