Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046930011> ?p ?o ?g. }
- W2046930011 endingPage "536" @default.
- W2046930011 startingPage "515" @default.
- W2046930011 abstract "Hepatitis C virus, a recently identified member of the family Flaviviridae, is an important cause of chronic viral hepatitis and cirrhosis. There are similarities in the nature of the immune response to this pathogen with immunity in other flavivirus and hepatotropic virus infections, such as hepatitis B. However, the high rate of viral persistence after primary hepatitis C infection, and the observation that neutralizing antibodies are not protective, would suggest that there are a number of important differences between hepatitis C, other flaviviruses, and hepatitis B. The phenomenon of quasispecies evolution and other viral factors have been proposed to contribute to immune evasion by hepatitis C virus. In the face of established persistent infection, virus‐specific cytotoxic T lymphocytes may exert some control over viral replication. However, these same effectors may also be responsible for the progressive liver damage characteristic of chronic hepatitis C infection. The nature of protective immunity, including the role of innate immune responses early after hepatitis C exposure, remains to be defined." @default.
- W2046930011 created "2016-06-24" @default.
- W2046930011 creator A5004304607 @default.
- W2046930011 creator A5017869449 @default.
- W2046930011 creator A5021516067 @default.
- W2046930011 creator A5054984686 @default.
- W2046930011 date "2001-12-01" @default.
- W2046930011 modified "2023-09-26" @default.
- W2046930011 title "Immunopathogenesis of hepatitis C virus infection" @default.
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