Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046959263> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2046959263 endingPage "201" @default.
- W2046959263 startingPage "197" @default.
- W2046959263 abstract "The binding of [3H]5-hydroxytryptamine (5-HT) to rat enteric membranes was inhibited by the inclusion of 5-HT 2-methyl-5-HT, 5-hydroxytryptophan, N,N,N-triethyltryptamine and 2-Br-N,N-diethyltryptamine in the incubation buffer. In contrast, tryptamine, 5-methoxytryptamine and 2-methyl-N,N-diethyltryptamine enhanced binding. Ascorbate and dithiothreitol facilitated and reduced binding at low and high concentrations respectively. Methysergide, tropisetron, paroxetine and pargyline failed to modify binding. However, following the establishment of [3H]5-HT binding, the subsequent addition of 5-HT and other agents failed to displace [3H]5-HT binding. Heat treatment of the membrane preparation also failed to modify [3H]5-HT binding. The latter findings of an irreversible and heat-insensitive binding indicate that the apparently high affinity ‘specific’ labelling of [3H]5-HT to rat enteric membranes does not represent receptor-bound [3H]5-HT. The complex interaction between [3H]5-HT and other agents may reflect oxidative events and problematic binding." @default.
- W2046959263 created "2016-06-24" @default.
- W2046959263 creator A5033052914 @default.
- W2046959263 creator A5036115757 @default.
- W2046959263 creator A5060211915 @default.
- W2046959263 date "1993-05-01" @default.
- W2046959263 modified "2023-09-23" @default.
- W2046959263 title "Problematical binding of [3H]5-hydroxytryptamine to rat gut myenteric membranes" @default.
- W2046959263 cites W11223074 @default.
- W2046959263 cites W1898351772 @default.
- W2046959263 cites W1992318904 @default.
- W2046959263 cites W1999379600 @default.
- W2046959263 cites W2002067584 @default.
- W2046959263 cites W2003745741 @default.
- W2046959263 cites W2004820363 @default.
- W2046959263 cites W2015464961 @default.
- W2046959263 cites W2028330142 @default.
- W2046959263 cites W2035977493 @default.
- W2046959263 cites W2059772079 @default.
- W2046959263 cites W2082454081 @default.
- W2046959263 cites W2160239489 @default.
- W2046959263 cites W2308049205 @default.
- W2046959263 cites W2415048922 @default.
- W2046959263 doi "https://doi.org/10.1016/0922-4106(93)90097-s" @default.
- W2046959263 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8335059" @default.
- W2046959263 hasPublicationYear "1993" @default.
- W2046959263 type Work @default.
- W2046959263 sameAs 2046959263 @default.
- W2046959263 citedByCount "1" @default.
- W2046959263 crossrefType "journal-article" @default.
- W2046959263 hasAuthorship W2046959263A5033052914 @default.
- W2046959263 hasAuthorship W2046959263A5036115757 @default.
- W2046959263 hasAuthorship W2046959263A5060211915 @default.
- W2046959263 hasConcept C107824862 @default.
- W2046959263 hasConcept C12554922 @default.
- W2046959263 hasConcept C170493617 @default.
- W2046959263 hasConcept C181199279 @default.
- W2046959263 hasConcept C185592680 @default.
- W2046959263 hasConcept C25642318 @default.
- W2046959263 hasConcept C2775864247 @default.
- W2046959263 hasConcept C2777067607 @default.
- W2046959263 hasConcept C2777135210 @default.
- W2046959263 hasConcept C2777824588 @default.
- W2046959263 hasConcept C2781005078 @default.
- W2046959263 hasConcept C41625074 @default.
- W2046959263 hasConcept C55493867 @default.
- W2046959263 hasConcept C86803240 @default.
- W2046959263 hasConceptScore W2046959263C107824862 @default.
- W2046959263 hasConceptScore W2046959263C12554922 @default.
- W2046959263 hasConceptScore W2046959263C170493617 @default.
- W2046959263 hasConceptScore W2046959263C181199279 @default.
- W2046959263 hasConceptScore W2046959263C185592680 @default.
- W2046959263 hasConceptScore W2046959263C25642318 @default.
- W2046959263 hasConceptScore W2046959263C2775864247 @default.
- W2046959263 hasConceptScore W2046959263C2777067607 @default.
- W2046959263 hasConceptScore W2046959263C2777135210 @default.
- W2046959263 hasConceptScore W2046959263C2777824588 @default.
- W2046959263 hasConceptScore W2046959263C2781005078 @default.
- W2046959263 hasConceptScore W2046959263C41625074 @default.
- W2046959263 hasConceptScore W2046959263C55493867 @default.
- W2046959263 hasConceptScore W2046959263C86803240 @default.
- W2046959263 hasIssue "3" @default.
- W2046959263 hasLocation W20469592631 @default.
- W2046959263 hasLocation W20469592632 @default.
- W2046959263 hasOpenAccess W2046959263 @default.
- W2046959263 hasPrimaryLocation W20469592631 @default.
- W2046959263 hasRelatedWork W2046959263 @default.
- W2046959263 hasRelatedWork W2066350260 @default.
- W2046959263 hasRelatedWork W2078690350 @default.
- W2046959263 hasRelatedWork W2080517416 @default.
- W2046959263 hasRelatedWork W2081523543 @default.
- W2046959263 hasRelatedWork W2082551067 @default.
- W2046959263 hasRelatedWork W2085830111 @default.
- W2046959263 hasRelatedWork W2105500940 @default.
- W2046959263 hasRelatedWork W2419498674 @default.
- W2046959263 hasRelatedWork W3146158776 @default.
- W2046959263 hasVolume "245" @default.
- W2046959263 isParatext "false" @default.
- W2046959263 isRetracted "false" @default.
- W2046959263 magId "2046959263" @default.
- W2046959263 workType "article" @default.