Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046972912> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2046972912 endingPage "25" @default.
- W2046972912 startingPage "21" @default.
- W2046972912 abstract "The fatty acid compositions of red blood cell (RBC) phospholipids from a patient with autistic spectrum disorder (ASD) had reduced percentages of highly unsaturated fatty acids (HUFA) compared to control samples. The percentage of HUFA in the RBC from the autistic patient was dramatically reduced (up to 70%) when the sample was stored for 6 weeks at −20°C. However, only minor HUFA reductions were recorded in control samples stored similarly, or when the autistic sample was stored at −80°C. A similar instability in RBC HUFA compositions upon storage at −20°C has been recorded in schizophrenic patients. In a number of other neurodevelopmental conditions, including attention deficit hyperactivity disorder (ADHD) and dyslexia, reduced concentrations of RBC HUFA have been recorded. The extent and nature of these aberrations require further assessment to determine a possible common biochemical origin of neurodevelopmental disorders in general. To facilitate this, a large scale assessment of RBC fatty acid compositions in patients with ASD, and related disorders, should be performed as a matter of urgency. Supplementing cells in culture with the tryptophan metabolite indole acrylic acid (IAA) affected the levels of cellular HUFA and prostaglandin production. Indole acroyl glycine (IAG), a metabolite of IAA excreted in urine, is found in high concentrations in patients with neurodevelopmental disorders including ASD, ADHD, dyslexia, Asperger's syndrome and obsessive compulsive disorder." @default.
- W2046972912 created "2016-06-24" @default.
- W2046972912 creator A5000914851 @default.
- W2046972912 creator A5014806457 @default.
- W2046972912 creator A5055137150 @default.
- W2046972912 creator A5059666445 @default.
- W2046972912 date "2000-07-01" @default.
- W2046972912 modified "2023-09-23" @default.
- W2046972912 title "Red blood cell fatty acid compositions in a patient with autistic spectrum disorder: a characteristic abnormality in neurodevelopmental disorders?" @default.
- W2046972912 cites W1481587329 @default.
- W2046972912 cites W1500405769 @default.
- W2046972912 cites W1597131590 @default.
- W2046972912 cites W1969820613 @default.
- W2046972912 cites W1977030256 @default.
- W2046972912 cites W1991506996 @default.
- W2046972912 cites W1992388910 @default.
- W2046972912 cites W1994139848 @default.
- W2046972912 cites W1994219221 @default.
- W2046972912 cites W1995253276 @default.
- W2046972912 cites W2014330045 @default.
- W2046972912 cites W2080927832 @default.
- W2046972912 cites W2097426501 @default.
- W2046972912 cites W2106198842 @default.
- W2046972912 cites W2119138947 @default.
- W2046972912 cites W2126403835 @default.
- W2046972912 cites W2143127986 @default.
- W2046972912 cites W2144138625 @default.
- W2046972912 cites W4236252899 @default.
- W2046972912 cites W4246878015 @default.
- W2046972912 doi "https://doi.org/10.1054/plef.2000.0186" @default.
- W2046972912 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10970708" @default.
- W2046972912 hasPublicationYear "2000" @default.
- W2046972912 type Work @default.
- W2046972912 sameAs 2046972912 @default.
- W2046972912 citedByCount "97" @default.
- W2046972912 countsByYear W20469729122012 @default.
- W2046972912 countsByYear W20469729122013 @default.
- W2046972912 countsByYear W20469729122014 @default.
- W2046972912 countsByYear W20469729122015 @default.
- W2046972912 countsByYear W20469729122016 @default.
- W2046972912 countsByYear W20469729122017 @default.
- W2046972912 countsByYear W20469729122018 @default.
- W2046972912 countsByYear W20469729122019 @default.
- W2046972912 countsByYear W20469729122020 @default.
- W2046972912 countsByYear W20469729122021 @default.
- W2046972912 crossrefType "journal-article" @default.
- W2046972912 hasAuthorship W2046972912A5000914851 @default.
- W2046972912 hasAuthorship W2046972912A5014806457 @default.
- W2046972912 hasAuthorship W2046972912A5055137150 @default.
- W2046972912 hasAuthorship W2046972912A5059666445 @default.
- W2046972912 hasConcept C118552586 @default.
- W2046972912 hasConcept C126322002 @default.
- W2046972912 hasConcept C134018914 @default.
- W2046972912 hasConcept C205778803 @default.
- W2046972912 hasConcept C2776703358 @default.
- W2046972912 hasConcept C2777477808 @default.
- W2046972912 hasConcept C2778228783 @default.
- W2046972912 hasConcept C2778538070 @default.
- W2046972912 hasConcept C2779388368 @default.
- W2046972912 hasConcept C71924100 @default.
- W2046972912 hasConceptScore W2046972912C118552586 @default.
- W2046972912 hasConceptScore W2046972912C126322002 @default.
- W2046972912 hasConceptScore W2046972912C134018914 @default.
- W2046972912 hasConceptScore W2046972912C205778803 @default.
- W2046972912 hasConceptScore W2046972912C2776703358 @default.
- W2046972912 hasConceptScore W2046972912C2777477808 @default.
- W2046972912 hasConceptScore W2046972912C2778228783 @default.
- W2046972912 hasConceptScore W2046972912C2778538070 @default.
- W2046972912 hasConceptScore W2046972912C2779388368 @default.
- W2046972912 hasConceptScore W2046972912C71924100 @default.
- W2046972912 hasIssue "1-2" @default.
- W2046972912 hasLocation W20469729121 @default.
- W2046972912 hasLocation W20469729122 @default.
- W2046972912 hasOpenAccess W2046972912 @default.
- W2046972912 hasPrimaryLocation W20469729121 @default.
- W2046972912 hasRelatedWork W1973752844 @default.
- W2046972912 hasRelatedWork W2337467669 @default.
- W2046972912 hasRelatedWork W2802697227 @default.
- W2046972912 hasRelatedWork W2952537492 @default.
- W2046972912 hasRelatedWork W2966214953 @default.
- W2046972912 hasRelatedWork W2983113363 @default.
- W2046972912 hasRelatedWork W3005935337 @default.
- W2046972912 hasRelatedWork W3143577379 @default.
- W2046972912 hasRelatedWork W3157136344 @default.
- W2046972912 hasRelatedWork W4243175822 @default.
- W2046972912 hasVolume "63" @default.
- W2046972912 isParatext "false" @default.
- W2046972912 isRetracted "false" @default.
- W2046972912 magId "2046972912" @default.
- W2046972912 workType "article" @default.