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- W2046986711 abstract "The kinetics and pathway of ethanol metabolism in endosperm tissues of the germinating castor bean-have been studied by incubating tissue slices with micromolar quantities of ethanol-1- 14 C and ethanol-2- 14 C. In short term experiments, ethanol- 14 C was incorporated into the organic acids and acidic amino acids. When the experimental period was increased up to 1 hour, large amounts of ethanol-2- 14 C were incorporated into the sugars, and ethanol-1- 14 C was extensively incorporated into the respiratory carbon dioxide. Incorporation of ethanol- 14 C was stimulated by incubation of the tissues with glyoxylate. Ethanol metabolism was markedly inhibited by iodoacetate and malonate. These inhibitors also changed the distribution of 14 C in the products isolated. Isotopic competition studies indicated that ethanol was incorporated into the acids of the glyoxylate and the tricarboxylic acid cycles at rates substantially lower than acetate.The results are interpreted as being consistent with a metabolism of ethanol mainly via the glyoxylate cycle with some cycling of ethanol carbon through the tricarboxylic acid cycle." @default.
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- W2046986711 date "1966-04-01" @default.
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- W2046986711 title "PARTICIPATION OF THE GLYOXYLATE CYCLE IN THE METABOLISM OF ETHANOL BY CASTOR BEAN ENDOSPERM TISSUES" @default.
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- W2046986711 doi "https://doi.org/10.1139/o66-052" @default.
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