FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2046999225> ?p ?o ?g. }

• W2046999225 endingPage "83" @default.
• W2046999225 startingPage "78" @default.
• W2046999225 abstract "We designed three types of transmembrane model peptides whose sequence originates from a frequently used model peptide KALP23, and we investigated their effects on phospholipid flip-flop. Time-resolved small-angle neutron scattering and a dithionite fluorescent quenching assay demonstrated that TMP-L, which has a fully hydrophobic transmembrane region, did not enhance phospholipid flip-flop, whereas TMP-K and TMP-E, which have Lys and Glu, respectively, in the center of their transmembrane regions, enhanced phospholipid flip-flop. Introduction of polar residues in the membrane-spanning helices is considered to produce a locally polar region and enable the lipid head group to interact with the polar side-chain inside the bilayers, thereby reducing the activation energy for the flip-flop. A bioinformatics approach revealed that acidic and basic residues account for 4.5% of the central region of the transmembrane domain in human ER membrane proteins. Therefore, polar residues in ER membrane proteins are considered to provide flippase-like activity." @default.
• W2046999225 created "2016-06-24" @default.
• W2046999225 creator A5001763350 @default.
• W2046999225 creator A5005220442 @default.
• W2046999225 creator A5007301301 @default.
• W2046999225 creator A5042205612 @default.
• W2046999225 creator A5076340186 @default.
• W2046999225 creator A5078252998 @default.
• W2046999225 creator A5080591970 @default.
• W2046999225 date "2013-06-01" @default.
• W2046999225 modified "2023-10-16" @default.
• W2046999225 title "Control of phospholipid flip-flop by transmembrane peptides" @default.
• W2046999225 cites W1975386547 @default.
• W2046999225 cites W1981010770 @default.
• W2046999225 cites W1981020955 @default.
• W2046999225 cites W1985584408 @default.
• W2046999225 cites W1990356838 @default.
• W2046999225 cites W2009110742 @default.
• W2046999225 cites W2016641591 @default.
• W2046999225 cites W2025406853 @default.
• W2046999225 cites W2046784147 @default.
• W2046999225 cites W2047051687 @default.
• W2046999225 cites W2055186281 @default.
• W2046999225 cites W2077167494 @default.
• W2046999225 cites W2097364162 @default.
• W2046999225 cites W2125872855 @default.
• W2046999225 cites W2138952800 @default.
• W2046999225 cites W2147531177 @default.
• W2046999225 doi "https://doi.org/10.1016/j.chemphys.2012.12.041" @default.
• W2046999225 hasPublicationYear "2013" @default.
• W2046999225 type Work @default.
• W2046999225 sameAs 2046999225 @default.
• W2046999225 citedByCount "23" @default.
• W2046999225 countsByYear W20469992252015 @default.
• W2046999225 countsByYear W20469992252016 @default.
• W2046999225 countsByYear W20469992252017 @default.
• W2046999225 countsByYear W20469992252018 @default.
• W2046999225 countsByYear W20469992252019 @default.
• W2046999225 countsByYear W20469992252020 @default.
• W2046999225 countsByYear W20469992252021 @default.
• W2046999225 countsByYear W20469992252022 @default.
• W2046999225 countsByYear W20469992252023 @default.
• W2046999225 crossrefType "journal-article" @default.
• W2046999225 hasAuthorship W2046999225A5001763350 @default.
• W2046999225 hasAuthorship W2046999225A5005220442 @default.
• W2046999225 hasAuthorship W2046999225A5007301301 @default.
• W2046999225 hasAuthorship W2046999225A5042205612 @default.
• W2046999225 hasAuthorship W2046999225A5076340186 @default.
• W2046999225 hasAuthorship W2046999225A5078252998 @default.
• W2046999225 hasAuthorship W2046999225A5080591970 @default.
• W2046999225 hasConcept C118892022 @default.
• W2046999225 hasConcept C121332964 @default.
• W2046999225 hasConcept C121745418 @default.
• W2046999225 hasConcept C12554922 @default.
• W2046999225 hasConcept C170493617 @default.
• W2046999225 hasConcept C185592680 @default.
• W2046999225 hasConcept C190283241 @default.
• W2046999225 hasConcept C24530287 @default.
• W2046999225 hasConcept C2776591724 @default.
• W2046999225 hasConcept C2777019660 @default.
• W2046999225 hasConcept C2778918659 @default.
• W2046999225 hasConcept C2779637612 @default.
• W2046999225 hasConcept C39944091 @default.
• W2046999225 hasConcept C41625074 @default.
• W2046999225 hasConcept C55493867 @default.
• W2046999225 hasConcept C62520636 @default.
• W2046999225 hasConcept C8010536 @default.
• W2046999225 hasConcept C86803240 @default.
• W2046999225 hasConcept C91881484 @default.
• W2046999225 hasConceptScore W2046999225C118892022 @default.
• W2046999225 hasConceptScore W2046999225C121332964 @default.
• W2046999225 hasConceptScore W2046999225C121745418 @default.
• W2046999225 hasConceptScore W2046999225C12554922 @default.
• W2046999225 hasConceptScore W2046999225C170493617 @default.
• W2046999225 hasConceptScore W2046999225C185592680 @default.
• W2046999225 hasConceptScore W2046999225C190283241 @default.
• W2046999225 hasConceptScore W2046999225C24530287 @default.
• W2046999225 hasConceptScore W2046999225C2776591724 @default.
• W2046999225 hasConceptScore W2046999225C2777019660 @default.
• W2046999225 hasConceptScore W2046999225C2778918659 @default.
• W2046999225 hasConceptScore W2046999225C2779637612 @default.
• W2046999225 hasConceptScore W2046999225C39944091 @default.
• W2046999225 hasConceptScore W2046999225C41625074 @default.
• W2046999225 hasConceptScore W2046999225C55493867 @default.
• W2046999225 hasConceptScore W2046999225C62520636 @default.
• W2046999225 hasConceptScore W2046999225C8010536 @default.
• W2046999225 hasConceptScore W2046999225C86803240 @default.
• W2046999225 hasConceptScore W2046999225C91881484 @default.
• W2046999225 hasFunder F4320320912 @default.
• W2046999225 hasFunder F4320322210 @default.
• W2046999225 hasLocation W20469992251 @default.
• W2046999225 hasOpenAccess W2046999225 @default.
• W2046999225 hasPrimaryLocation W20469992251 @default.
• W2046999225 hasRelatedWork W2027484237 @default.
• W2046999225 hasRelatedWork W2046999225 @default.
• W2046999225 hasRelatedWork W2107646932 @default.
• W2046999225 hasRelatedWork W2156897191 @default.
• W2046999225 hasRelatedWork W2161536338 @default.

• next