FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047026181> ?p ?o ?g. }

• W2047026181 endingPage "76" @default.
• W2047026181 startingPage "65" @default.
• W2047026181 abstract "The genotoxicity of endogenously formed N-nitrosamines from secondary amines and sodium nitrite (NaNO(2)) was evaluated in multiple organs of mice, using comet assay. Groups of four male mice were orally given dimethylamine, proline, and morpholine simultaneously with NaNO(2). The stomach, colon, liver, kidney, urinary bladder, lung, brain, and bone marrow were sampled 3 and 24 h after these compounds had been ingested. Although secondary amines and the NaNO(2) tested did not yield DNA damage in any of the organs tested, DNA damage was observed mainly in the liver following simultaneous oral ingestion of these compounds. The administration within a 60 min interval also yielded hepatic DNA damage. It is considered that DNA damage induced in mouse organs with the coexistence of amines and nitrite in the acidic stomach is due to endogenously formed nitrosamines. Ascorbic acid reduced the liver DNA damage induced by morpholine and NaNO(2). Reductions in hepatic genotoxicity of endogenously formed N-nitrosomorpholine by tea polyphenols, such as catechins and theaflavins, and fresh apple, grape, and orange juices were more effective than was by ascorbic acid. In contrast with the antimutagenicity of ascorbic acid in the liver, ascorbic acid yielded stomach DNA damage in the presence of NaNO(2) (in the presence and absence of morpholine). Even if ascorbic acid acts as an antimutagen in the liver, nitric oxide (NO) formed from the reduction of NaNO(2) by ascorbic acid damaged stomach DNA." @default.
• W2047026181 created "2016-06-24" @default.
• W2047026181 creator A5007918106 @default.
• W2047026181 creator A5013599536 @default.
• W2047026181 creator A5021926265 @default.
• W2047026181 creator A5028759177 @default.
• W2047026181 creator A5028820649 @default.
• W2047026181 creator A5032994178 @default.
• W2047026181 creator A5058213003 @default.
• W2047026181 creator A5071129667 @default.
• W2047026181 date "2003-08-01" @default.
• W2047026181 modified "2023-10-16" @default.
• W2047026181 title "Detection of in vivo genotoxicity of endogenously formed N-nitroso compounds and suppression by ascorbic acid, teas and fruit juices" @default.
• W2047026181 cites W1642047822 @default.
• W2047026181 cites W1938483500 @default.
• W2047026181 cites W1967836873 @default.
• W2047026181 cites W1972654812 @default.
• W2047026181 cites W1989790202 @default.
• W2047026181 cites W1996690314 @default.
• W2047026181 cites W1996862854 @default.
• W2047026181 cites W2006108963 @default.
• W2047026181 cites W2008334977 @default.
• W2047026181 cites W2008677473 @default.
• W2047026181 cites W2009601408 @default.
• W2047026181 cites W2009678366 @default.
• W2047026181 cites W2012677104 @default.
• W2047026181 cites W2013766389 @default.
• W2047026181 cites W2016144648 @default.
• W2047026181 cites W2016885914 @default.
• W2047026181 cites W2019318714 @default.
• W2047026181 cites W2028296755 @default.
• W2047026181 cites W2041791338 @default.
• W2047026181 cites W2043562592 @default.
• W2047026181 cites W2046219406 @default.
• W2047026181 cites W2048780820 @default.
• W2047026181 cites W2052350574 @default.
• W2047026181 cites W2065267035 @default.
• W2047026181 cites W2065768538 @default.
• W2047026181 cites W2071825506 @default.
• W2047026181 cites W2074315475 @default.
• W2047026181 cites W2086451070 @default.
• W2047026181 cites W2091293291 @default.
• W2047026181 cites W2095177409 @default.
• W2047026181 cites W2100618800 @default.
• W2047026181 cites W2124347218 @default.
• W2047026181 cites W2125113789 @default.
• W2047026181 cites W2129016270 @default.
• W2047026181 cites W2168237329 @default.
• W2047026181 cites W2321692081 @default.
• W2047026181 cites W2057231941 @default.
• W2047026181 doi "https://doi.org/10.1016/s1383-5718(03)00156-6" @default.
• W2047026181 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12948815" @default.
• W2047026181 hasPublicationYear "2003" @default.
• W2047026181 type Work @default.
• W2047026181 sameAs 2047026181 @default.
• W2047026181 citedByCount "54" @default.
• W2047026181 countsByYear W20470261812012 @default.
• W2047026181 countsByYear W20470261812013 @default.
• W2047026181 countsByYear W20470261812014 @default.
• W2047026181 countsByYear W20470261812015 @default.
• W2047026181 countsByYear W20470261812016 @default.
• W2047026181 countsByYear W20470261812017 @default.
• W2047026181 countsByYear W20470261812019 @default.
• W2047026181 countsByYear W20470261812020 @default.
• W2047026181 countsByYear W20470261812021 @default.
• W2047026181 countsByYear W20470261812023 @default.
• W2047026181 crossrefType "journal-article" @default.
• W2047026181 hasAuthorship W2047026181A5007918106 @default.
• W2047026181 hasAuthorship W2047026181A5013599536 @default.
• W2047026181 hasAuthorship W2047026181A5021926265 @default.
• W2047026181 hasAuthorship W2047026181A5028759177 @default.
• W2047026181 hasAuthorship W2047026181A5028820649 @default.
• W2047026181 hasAuthorship W2047026181A5032994178 @default.
• W2047026181 hasAuthorship W2047026181A5058213003 @default.
• W2047026181 hasAuthorship W2047026181A5071129667 @default.
• W2047026181 hasConcept C114246631 @default.
• W2047026181 hasConcept C143425029 @default.
• W2047026181 hasConcept C178790620 @default.
• W2047026181 hasConcept C185592680 @default.
• W2047026181 hasConcept C2776639595 @default.
• W2047026181 hasConcept C2777395278 @default.
• W2047026181 hasConcept C2777633056 @default.
• W2047026181 hasConcept C2778959862 @default.
• W2047026181 hasConcept C2780358455 @default.
• W2047026181 hasConcept C2781056017 @default.
• W2047026181 hasConcept C2781422964 @default.
• W2047026181 hasConcept C29730261 @default.
• W2047026181 hasConcept C2986274086 @default.
• W2047026181 hasConcept C31903555 @default.
• W2047026181 hasConcept C552990157 @default.
• W2047026181 hasConcept C55493867 @default.
• W2047026181 hasConceptScore W2047026181C114246631 @default.
• W2047026181 hasConceptScore W2047026181C143425029 @default.
• W2047026181 hasConceptScore W2047026181C178790620 @default.
• W2047026181 hasConceptScore W2047026181C185592680 @default.
• W2047026181 hasConceptScore W2047026181C2776639595 @default.
• W2047026181 hasConceptScore W2047026181C2777395278 @default.
• W2047026181 hasConceptScore W2047026181C2777633056 @default.

• next