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- W2047029298 abstract "Abstract The time course of NA depletion and organ contents of α-MPT after repeated doses of the methyl ester of α-MPT (H44/68) was studied in the heart, innervated and decentralized submaxillary gland, seminal vesicle and vas deferens of the rat. A definite difference in effect of α-MPT on the different peripheral NA stores was demonstrated. While the innervated hearts and submaxillary glands had lost 22 and 36% of their NA respectively in 10 hrs, the short adrenergic neurons of the vas deferens and the seminal vesicle retained about normal NA levels even 16 hrs after repeated doses of α-MPT, despite very high organ concentrations of the drug and regardless of whether the adrenergic nerve supply via the hypogastric nerve was intact or not. Possible mechanisms for this resistance to α-MPT are discussed." @default.
- W2047029298 created "2016-06-24" @default.
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- W2047029298 date "1970-11-01" @default.
- W2047029298 modified "2023-10-01" @default.
- W2047029298 title "Comparison of the effects of α-methyltyrosine on the nor-adrenaline stores of different peripheral organs of the rat" @default.
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- W2047029298 doi "https://doi.org/10.1016/0024-3205(70)90159-1" @default.
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