FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2047030375> ?p ?o ?g. }

• W2047030375 endingPage "295" @default.
• W2047030375 startingPage "295" @default.
• W2047030375 abstract "Inhaled corticosteroid use in patients with chronic obstructive pulmonary disease and the risk of pneumonia: a retrospective claims data analysis Barbara P Yawn,1 Yunfeng Li,2 Haijun Tian,2 Jie Zhang,2 Steve Arcona,2 Kristijan H Kahler2 1Department of Research, Olmsted Medical Center, Rochester, MN, USA; 2Department of Health Economics and Outcomes Research, Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA Background: The use of inhaled corticosteroids in patients with chronic obstructive pulmonary disease (COPD) has been associated with an increased risk of pneumonia in controlled clinical trials and case-control analyses. Objective: Using claims databases as a research model of real-world diagnosis and treatment, to determine if the use and dose of inhaled corticosteroids (ICS) among patients with newly diagnosed COPD are associated with increased risk of pneumonia. Patients and methods: This was a retrospective cohort analysis of patients diagnosed with COPD between January 01, 2006 and September 30, 2010, drawn from databases (years 2006–2010). Patients (aged ≥45 years) were followed until first pneumonia diagnosis, end of benefit enrollment, or December 31, 2010, whichever was earliest. A Cox proportional hazard model was used to assess the association of ICS use and risk of pneumonia, controlling for baseline characteristics. Daily ICS use was classified into low, medium, and high doses (1 µg–499 µg, 500 µg–999 µg, and ≥1000 µg fluticasone equivalents daily) and was modeled as a time-dependent variable. Results: Among 135,445 qualifying patients with a total of 243,097 person-years, there were 1020 pneumonia incidences out of 5677 person-years on ICS (crude incidence rate, 0.180 per person-year), and 27,730 pneumonia incidences out of 237,420 person-years not on ICS (crude incidence rate, 0.117 per person-year). ICS use was associated with a dose-related increase in risk of pneumonia, with adjusted hazard ratios (versus no use; (95% confidence interval) of 1.38 (1.27–1.49) for low-dose users, 1.69 (1.52–1.88) for medium-dose users, and 2.57 (1.98–3.33) for high-dose users (P < 0.01 versus no use and between doses). Conclusion: The use of ICS in newly diagnosed patients with COPD is potentially associated with a dose-related increase in the risk of pneumonia. Keywords: COPD, ICS, LABA, pneumonia" @default.
• W2047030375 created "2016-06-24" @default.
• W2047030375 creator A5005260055 @default.
• W2047030375 creator A5059135262 @default.
• W2047030375 creator A5073501391 @default.
• W2047030375 creator A5074784153 @default.
• W2047030375 creator A5076124157 @default.
• W2047030375 creator A5084954969 @default.
• W2047030375 date "2013-06-01" @default.
• W2047030375 modified "2023-10-17" @default.
• W2047030375 title "Inhaled corticosteroid use in patients with chronic obstructive pulmonary disease and the risk of pneumonia: a retrospective claims data analysis" @default.
• W2047030375 cites W1914317343 @default.
• W2047030375 cites W1982938776 @default.
• W2047030375 cites W1983772324 @default.
• W2047030375 cites W1986646533 @default.
• W2047030375 cites W1987213251 @default.
• W2047030375 cites W1987555297 @default.
• W2047030375 cites W1990074509 @default.
• W2047030375 cites W1991648511 @default.
• W2047030375 cites W2007503447 @default.
• W2047030375 cites W2019271924 @default.
• W2047030375 cites W2019720524 @default.
• W2047030375 cites W2034740881 @default.
• W2047030375 cites W2035582694 @default.
• W2047030375 cites W2035818402 @default.
• W2047030375 cites W2059474976 @default.
• W2047030375 cites W2060364778 @default.
• W2047030375 cites W2063348549 @default.
• W2047030375 cites W2077672954 @default.
• W2047030375 cites W2091215576 @default.
• W2047030375 cites W2096365438 @default.
• W2047030375 cites W2100738224 @default.
• W2047030375 cites W2105577900 @default.
• W2047030375 cites W2110947112 @default.
• W2047030375 cites W2120629366 @default.
• W2047030375 cites W2127370507 @default.
• W2047030375 cites W2129182118 @default.
• W2047030375 cites W2131247884 @default.
• W2047030375 cites W2133343848 @default.
• W2047030375 cites W2134492231 @default.
• W2047030375 cites W2136133799 @default.
• W2047030375 cites W2138693512 @default.
• W2047030375 cites W2142724633 @default.
• W2047030375 cites W2145466675 @default.
• W2047030375 cites W2146877487 @default.
• W2047030375 cites W2152051934 @default.
• W2047030375 cites W2154692607 @default.
• W2047030375 cites W2156749094 @default.
• W2047030375 cites W2156883692 @default.
• W2047030375 cites W2158714986 @default.
• W2047030375 cites W2160421825 @default.
• W2047030375 cites W2169927995 @default.
• W2047030375 cites W2209473605 @default.
• W2047030375 cites W2318572138 @default.
• W2047030375 doi "https://doi.org/10.2147/copd.s42366" @default.
• W2047030375 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3699136" @default.
• W2047030375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23836970" @default.
• W2047030375 hasPublicationYear "2013" @default.
• W2047030375 type Work @default.
• W2047030375 sameAs 2047030375 @default.
• W2047030375 citedByCount "76" @default.
• W2047030375 countsByYear W20470303752013 @default.
• W2047030375 countsByYear W20470303752014 @default.
• W2047030375 countsByYear W20470303752015 @default.
• W2047030375 countsByYear W20470303752016 @default.
• W2047030375 countsByYear W20470303752017 @default.
• W2047030375 countsByYear W20470303752018 @default.
• W2047030375 countsByYear W20470303752019 @default.
• W2047030375 countsByYear W20470303752020 @default.
• W2047030375 countsByYear W20470303752021 @default.
• W2047030375 countsByYear W20470303752022 @default.
• W2047030375 countsByYear W20470303752023 @default.
• W2047030375 crossrefType "journal-article" @default.
• W2047030375 hasAuthorship W2047030375A5005260055 @default.
• W2047030375 hasAuthorship W2047030375A5059135262 @default.
• W2047030375 hasAuthorship W2047030375A5073501391 @default.
• W2047030375 hasAuthorship W2047030375A5074784153 @default.
• W2047030375 hasAuthorship W2047030375A5076124157 @default.
• W2047030375 hasAuthorship W2047030375A5084954969 @default.
• W2047030375 hasBestOaLocation W20470303751 @default.
• W2047030375 hasConcept C126322002 @default.
• W2047030375 hasConcept C167135981 @default.
• W2047030375 hasConcept C207103383 @default.
• W2047030375 hasConcept C2776780178 @default.
• W2047030375 hasConcept C2776804153 @default.
• W2047030375 hasConcept C2777914695 @default.
• W2047030375 hasConcept C2779028295 @default.
• W2047030375 hasConcept C44249647 @default.
• W2047030375 hasConcept C71924100 @default.
• W2047030375 hasConceptScore W2047030375C126322002 @default.
• W2047030375 hasConceptScore W2047030375C167135981 @default.
• W2047030375 hasConceptScore W2047030375C207103383 @default.
• W2047030375 hasConceptScore W2047030375C2776780178 @default.
• W2047030375 hasConceptScore W2047030375C2776804153 @default.
• W2047030375 hasConceptScore W2047030375C2777914695 @default.
• W2047030375 hasConceptScore W2047030375C2779028295 @default.
• W2047030375 hasConceptScore W2047030375C44249647 @default.
• W2047030375 hasConceptScore W2047030375C71924100 @default.

• next