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- W2047046988 abstract "It has been 100 years since the concept of pH (1909-2009) was “invented” by the Danish chemist-mathematician Søren Peter Lauritz Sørensen (1868-1939) in the chemistry laboratories of the Carlsberg Brewery in Copenhagen. The anniversary provides an opportunity to examine the crucial importance in human life of acid-base balance. The authors review the historical process that led to the creation of the pH scale, with citation of passages from the original work of Sørensen published 100 years ago. This is followed by a critical analysis of the debate regarding the use of logarithms to measure hydrogen ion concentrations based on data from scientific papers published over the past 50 years (1960-2010). The authors conclude that the concept of acid-base balance can be approached and taught in a simpler, more exciting, and even pleasant fashion without using the infamous and abstruse Henderson-Hasselbalch equation. The whole rationale underlying the understanding and clinical application of this vital topic is clearly and unquestionably inherent simpler, more manageable formula introduced by Henderson (without logs), which is useful and quite adequate for use in medical education." @default.
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- W2047046988 date "2011-09-01" @default.
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- W2047046988 title "Il centenario del pH (1909-2009). Ma in medicina, è proprio indispensabile utilizzare i logaritmi negativi per misurare gli idrogenioni? Parte I" @default.
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- W2047046988 doi "https://doi.org/10.1016/j.itjm.2011.02.009" @default.
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